Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8735122 | 0.82 | LMNA (0.53) | KMT2AMEN1LMNAEPHX2MAPT | |
| SCHEMBL7149195 | 0.77 | ALDH1A1 (0.52) | RAB9AKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL7147959 | 0.77 | ALDH1A1 (0.56) | RAB9AKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL29158541 | 0.74 | PLK1 (0.46) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL9610938 | 0.74 | KMT2A (0.74) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL10787828 | 0.73 | NPC1 (0.41) | NPC1RAB9ALMNAMAPTALDH1A1 | |
| SCHEMBL13866389 | 0.73 | SMN1; SMN2 (0.51) | NPC1RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL8432209 | 0.73 | ALDH1A1 (0.48) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL10140460 | 0.73 | CYP4F2 (0.50) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL29158545 | 0.73 | PLK1 (0.44) | RAB9AKMT2AMEN1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020238375-A1 | FLUORESCENT COMPOUND HAVING AFFINITY WITH Aβ OLIGOMER, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国药科大学 | 2020-12-03 | — | — | WO | disclosed |