Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20677801 | 0.89 | GBA1 (0.45) | LMNAEPHX2CES2CES1AKR1B1 | |
| SCHEMBL1155730 | 0.84 | FAAH (0.55) | LMNAEPHX2CES2CES1AKR1B1 | |
| SCHEMBL22720209 | 0.82 | NPC1 (0.44) | LMNAEPHX2MEN1KMT2AALDH1A1 | |
| SCHEMBL51367 | 0.80 | CES1 (0.64) | LMNAEPHX2CES2CES1AKR1B1 | |
| SCHEMBL9111034 | 0.78 | CES1 (0.61) | LMNAEPHX2CES2CES1AKR1B1 | |
| SCHEMBL6363616 | 0.78 | CES1 (0.61) | LMNAEPHX2CES2CES1AKR1B1 | |
| SCHEMBL800064 | 0.77 | EPHX2 (0.56) | LMNAEPHX2CES2CES1AKR1B1 | |
| SCHEMBL4656202 | 0.77 | ALDH1A1 (0.56) | LMNAEPHX2CES2CES1AKR1B1 | |
| SCHEMBL3966085 | 0.76 | AKR1B1 (0.65) | LMNAEPHX2CES2CES1AKR1B1 | |
| SCHEMBL163232 | 0.76 | EPHX2 (0.59) | EPHX2CES2CES1AKR1B1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668258-B1 | Process for the preparation of 1-cyclopropylalkane-1,3-diones | HUELS CHEMISCHE WERKE AG (DE) | 1998-04-15 | — | — | EP | disclosed |
| US-5545762-A | REACTING CYCLOPROPYL ALKYL KETONE WITH CARBOXYLIC ESTER IN THE PRESENCE OF AN ALKALI METAL ALCOHOLATE | HUELS AKTIENGESELLSCHAFT (DE) | 1996-08-13 | — | — | US | disclosed |
| EP-0668258-A1 | Process for the preparation of 1-cyclopropylalkane-1,3-diones | HÜLS AKTIENGESELLSCHAFT (DE) | 1995-08-23 | — | — | EP | disclosed |