Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPY2R | P49146 | 1/20 | 0.30 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28530744 | 0.89 | TLR9 (0.35) | HTR2CSLC6A4HTR2AALDH1A1SMN1; SMN2 | |
| SCHEMBL28544155 | 0.89 | TLR9 (0.35) | HTR2CSLC6A4HTR2AALDH1A1SMN1; SMN2 | |
| SCHEMBL22720265 | 0.85 | TLR9 (0.40) | TLR9TLR7 | |
| SCHEMBL22724634 | 0.76 | KRAS (0.39) | HTR2CSLC6A4HTR2ATLR9TLR7 | |
| SCHEMBL22720270 | 0.69 | KRAS (0.37) | — | |
| SCHEMBL28537273 | 0.67 | TLR9 (0.35) | HTR2CSLC6A4TLR9TLR7 | |
| SCHEMBL18128721 | 0.64 | KRAS (0.38) | LIMK2 | |
| SCHEMBL2760636 | 0.64 | DRD2 (0.51) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL18128367 | 0.63 | KRAS (0.36) | ALDH1A1LIMK2 | |
| SCHEMBL12454614 | 0.62 | RIPK1 (0.46) | HTR2CSLC6A4HTR2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239123-A1 | AROMATIC HETEROCYCLIC DERIVATIVE MODULATOR AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-03 | — | — | WO | disclosed |