Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 16/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28542868 | 0.93 | KRAS (0.39) | KRASSOS1 | |
| SCHEMBL28542866 | 0.93 | KRAS (0.39) | KRASSOS1 | |
| SCHEMBL22720270 | 0.84 | KRAS (0.37) | KRASSOS1 | |
| SCHEMBL22720285 | 0.84 | KRAS (0.42) | KRASGPR119 | |
| SCHEMBL22720279 | 0.82 | TLR9 (0.43) | TLR9GPR119 | |
| SCHEMBL22720272 | 0.82 | KRAS (0.43) | KRASSOS1 | |
| SCHEMBL30957839 | 0.82 | KRAS (0.42) | KRASOPRM1OPRD1OGFRL1GPR119 | |
| SCHEMBL22720307 | 0.82 | KRAS (0.42) | KRASOPRM1OPRD1OGFRL1GPR119 | |
| SCHEMBL22724618 | 0.82 | KRAS (0.42) | KRASOPRM1OPRD1OGFRL1GPR119 | |
| SCHEMBL22720271 | 0.79 | KRAS (0.46) | KRASGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239123-A1 | AROMATIC HETEROCYCLIC DERIVATIVE MODULATOR AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-03 | — | — | WO | disclosed |
| WO-2020239123-A1 | AROMATIC HETEROCYCLIC DERIVATIVE MODULATOR AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-03 | — | — | WO | disclosed |