Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.36 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP1 | P63208 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22720268 | 0.82 | KRAS (0.39) | TLR9GPR119 | |
| SCHEMBL22724587 | 0.78 | TLR9 (0.44) | TLR9TLR7SMPD3GBA1CKS1B | |
| SCHEMBL22720236 | 0.78 | TLR9 (0.44) | TLR9TLR7SMPD3GBA1CKS1B | |
| SCHEMBL22720265 | 0.77 | TLR9 (0.40) | TLR9TLR7GPR119ACHE | |
| SCHEMBL22720228 | 0.76 | TLR9 (0.42) | TLR9TLR7SMPD3GPR119GBA1 | |
| SCHEMBL21734104 | 0.70 | GBA1 (0.44) | TLR9GPR119GBA1CKS1BSKP1 | |
| SCHEMBL19636828 | 0.69 | TLR9 (0.40) | TLR9TLR7GPR119GBA1CKS1B | |
| SCHEMBL22873609 | 0.68 | GPR119 (0.55) | TLR9SMPD3GPR119GBA1CKS1B | |
| SCHEMBL31652099 | 0.68 | TLR9 (0.54) | TLR9TLR7SMPD3GPR119GBA1 | |
| SCHEMBL5851554 | 0.67 | P2RY12 (0.48) | TLR9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239123-A1 | AROMATIC HETEROCYCLIC DERIVATIVE MODULATOR AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-03 | — | — | WO | disclosed |