Diphenylmethane

Diphenylmethane

SCHEMBL22720596

O=C(O)c1cccc(-c2cccc(C(=O)O)c2C(=O)O)c1C(=O)O.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.54
HNF4A P41235 2/20 0.51
PTPN1 P18031 4/20 0.50
ACMSD Q8TDX5 1/20 0.49
PTPN2 P17706 2/20 0.49
PTPN6 P29350 2/20 0.49
AKR1C3 P42330 1/20 0.48
ALDH1A1 P00352 4/20 0.48
ALOX15 P16050 1/20 0.48
TSHR P16473 1/20 0.47
CALM1 P0DP23 1/20 0.46
MYC P01106 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
HSD17B10 Q99714 1/20 0.46
PLA2G2A P14555 1/20 0.46
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9550396 0.87 FOLH1 (0.48) FOLH1HNF4APTPN1ACMSDPTPN2
SCHEMBL5321232 0.86 ALDH1A1 (0.59) FOLH1HNF4AAKR1C3ALDH1A1ALOX15
SCHEMBL6941870 0.86 ALDH1A1 (0.59) FOLH1HNF4AAKR1C3ALDH1A1ALOX15
SCHEMBL5321419 0.86 ALDH1A1 (0.59) FOLH1HNF4AAKR1C3ALDH1A1ALOX15
SCHEMBL63603 0.85 HSD17B10 (0.58) FOLH1HNF4AAKR1C3ALDH1A1ALOX15
SCHEMBL809021 0.84 FOLH1 (0.61) FOLH1HNF4AAKR1C3ALDH1A1ALOX15
Water SCHEMBL7131144 0.83 HSD17B10 (0.56) FOLH1HNF4AAKR1C3ALDH1A1ALOX15
SCHEMBL5554145 0.83 HSD17B10 (0.56) FOLH1HNF4AAKR1C3ALDH1A1ALOX15
SCHEMBL200212 0.83 TSHR (0.59) FOLH1HNF4APTPN1PTPN2PTPN6
SCHEMBL343520 0.81 TSHR (0.57) FOLH1HNF4APTPN1PTPN2PTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020238731-A1 BICYCLIC AMMONIUM ION POLYBENZIMIDAZOLE, ANION EXCHANGE MEMBRANE, PREPARATION METHOD THEREFOR AND USE THEREOF 大连理工大学 2020-12-03 WO disclosed