Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.51 |
| ▸ | CDK8 | P49336 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.45 |
| ▸ | WNT3A | P56704 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2278323 | 0.90 | LOXL2 (0.52) | LOXL2CYP4F2CYP4A11CDK8ABL1 | |
| SCHEMBL18941059 | 0.88 | ABL1 (0.49) | LOXL2CYP4A11ABL1SRCCTNNB1 | |
| SCHEMBL2275779 | 0.84 | CTNNB1 (0.52) | NPC1RAB9ACTNNB1WNT3AMAPT | |
| SCHEMBL18941074 | 0.81 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2MAPTNFATC1 | |
| SCHEMBL103794 | 0.80 | TUBB4A (0.58) | CDK8ABL1NPC1RAB9ACTNNB1 | |
| SCHEMBL29377304 | 0.80 | TUBB4A (0.58) | CDK8ABL1NPC1RAB9ACTNNB1 | |
| SCHEMBL18941275 | 0.80 | RXFP1 (0.58) | NPC1RAB9ASMN1; SMN2MAPTNFATC1 | |
| SCHEMBL18941260 | 0.79 | NPC1 (0.63) | NPC1RAB9ACTNNB1WNT3AMAPT | |
| Ammonia Solution, Strong SCHEMBL28339305 | 0.79 | TUBB4A (0.57) | CDK8ABL1NPC1RAB9ACTNNB1 | |
| Hydrochloric Acid SCHEMBL28263909 | 0.79 | TUBB4A (0.57) | CDK8ABL1NPC1RAB9ACTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455516-B2 | HIV-1 fusion inhibitors and methods | TOURO UNIVERSITY (US) | 2013-06-04 | — | — | US | disclosed |
| US-20110190343-A1 | HIV-1 FUSION INHIBITORS AND METHODS | TOURO UNIVERSITY (US) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190343-A1 | HIV-1 FUSION INHIBITORS AND METHODS | FLI1, API5, MAVS | LOXL2 4691/4885CYP4F2 1877/4885CYP4A11 4534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.