Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CCND2 | P30279 | 1/20 | 0.43 |
| ▸ | CCND3 | P30281 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 4/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31743093 | 0.79 | BRPF1 (0.59) | HTR6LDHAPGRESR1ESR2 | |
| SCHEMBL29941410 | 0.78 | CA12 (0.57) | CDK4CCND1CCND2CCND3MEN1 | |
| SCHEMBL11924989 | 0.78 | CA12 (0.57) | CDK4CCND1CCND2CCND3MEN1 | |
| SCHEMBL9498050 | 0.76 | LDHA (0.59) | HTR6LDHAPGRESR1ESR2 | |
| SCHEMBL11910684 | 0.73 | CASR (0.48) | CASRLDHAEGFRNR1I2ADRA2A | |
| SCHEMBL12794236 | 0.71 | POLB (0.64) | PGRLMNA | |
| SCHEMBL24667522 | 0.70 | CASR (0.46) | CASREGFRNR1I2ADRA2AADORA3 | |
| SCHEMBL31743122 | 0.70 | BRPF1 (0.61) | HTR6LDHAPGRIDH1KMT2A | |
| SCHEMBL18523561 | 0.70 | HTR4 (0.43) | EGFRNR1I2ADRA2AADORA3TBXA2R | |
| SCHEMBL21077038 | 0.69 | NR1I2 (0.47) | CASREGFRNR1I2ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020243519-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2020-12-03 | — | — | WO | disclosed |