Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 10/20 | 0.59 |
| ▸ | BRD4 | O60885 | 3/20 | 0.59 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.59 |
| ▸ | BRD1 | O95696 | 4/20 | 0.54 |
| ▸ | BRPF3 | Q9ULD4 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31743122 | 0.88 | BRPF1 (0.61) | BRPF1BRD4BRD9CA12CA9 | |
| SCHEMBL16573984 | 0.86 | BRPF1 (0.57) | BRPF1BRD4BRD9CA12CA9 | |
| SCHEMBL9498050 | 0.83 | LDHA (0.59) | HTR6LDHAPGRESR1ESR2 | |
| SCHEMBL7271260 | 0.82 | CYP11B2 (0.56) | BRPF1GRM2PGR | |
| SCHEMBL22725631 | 0.79 | CASR (0.45) | BRD4KMT2AGRM2HTR6LDHA | |
| SCHEMBL18713707 | 0.79 | BRPF1 (0.49) | BRPF1BRD4BRD9CA12CA9 | |
| SCHEMBL29967380 | 0.75 | BRPF1 (1.00) | BRPF1BRD4BRD9CA12CA9 | |
| SCHEMBL248619 | 0.75 | BRPF1 (1.00) | BRPF1BRD4BRD9CA12CA9 | |
| SCHEMBL18000168 | 0.75 | KMT2A (0.53) | KMT2AGRM2HTR6HSD11B1LDHA | |
| SCHEMBL422084 | 0.74 | BRPF1 (0.65) | BRPF1BRD4BRD9CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12496297-B1 | Compositions of autophagy modulating agents and uses thereof | WASHINGTON UNIVERSITY (US) | 2025-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12496297-B1 | Compositions of autophagy modulating agents and uses thereof | BECN1, TFEB, ATG7 | BRPF1 1803/4885BRD4 2141/4885BRD9 2950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.