Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | TRPM2 | O94759 | 5/20 | 0.54 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2272607 | 1.00 | MAPT (0.57) | MAPTTRPM2LTB4RHDAC2CA12 | |
| SCHEMBL2269335 | 0.81 | TRPM2 (0.75) | MAPTTRPM2LTB4RHDAC2TRPA1 | |
| SCHEMBL2269338 | 0.81 | TRPM2 (0.75) | MAPTTRPM2LTB4RHDAC2TRPA1 | |
| SCHEMBL2274808 | 0.81 | HDAC2 (0.74) | MAPTHDAC2MEN1KMT2ANPC1 | |
| SCHEMBL2271170 | 0.78 | TRPM2 (0.70) | MAPTTRPM2LTB4RHDAC2TRPA1 | |
| SCHEMBL2271172 | 0.78 | TRPM2 (0.70) | MAPTTRPM2LTB4RHDAC2TRPA1 | |
| SCHEMBL2269533 | 0.76 | HDAC2 (0.64) | MAPTHDAC2TP53MEN1KMT2A | |
| SCHEMBL2277736 | 0.76 | TRPM2 (0.63) | MAPTTRPM2LTB4RTRPA1TRPM8 | |
| SCHEMBL2277734 | 0.76 | TRPM2 (0.63) | MAPTTRPM2LTB4RTRPA1TRPM8 | |
| SCHEMBL31153395 | 0.75 | PELI1 (0.68) | MAPTTRPM2LTB4RTRPA1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7999132-B2 | Anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2011-08-16 | — | — | US | disclosed |
| US-20090240052-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| EP-1820795-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090240052-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | MMP13, MMP26, MMP11 | MAPT 4824/4885TRPM2 3539/4885LTB4R 2902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.