Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22728309 | 0.80 | KDM4C (0.35) | MEN1KMT2AOPRL1 | |
| SCHEMBL22728386 | 0.80 | OPRL1 (0.36) | SLC6A4SLC6A2OPRL1DRD2 | |
| SCHEMBL7135459 | 0.72 | HCRTR2 (0.45) | SLC6A4SLC6A2SLC6A3LMNAHCRTR2 | |
| SCHEMBL28206834 | 0.71 | PTGDR2 (0.44) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL22728321 | 0.71 | IDO1 (0.42) | SLC6A4SLC6A2KMT2ALMNA | |
| SCHEMBL954765 | 0.71 | ALDH1A1 (0.42) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| Formaldehyde SCHEMBL27876727 | 0.68 | PTGDR2 (0.44) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL2913534 | 0.68 | SLC6A2 (0.42) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL22728302 | 0.68 | RIPK1 (0.41) | — | |
| SCHEMBL5821254 | 0.67 | PTGDR2 (0.46) | SLC6A4SLC6A2SLC6A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020243027-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | SAGE THERAPEUTICS, INC. (US) | 2020-12-03 | — | — | WO | disclosed |