Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 14/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22728309 | 0.83 | KDM4C (0.35) | OPRL1PTGDR2 | |
| SCHEMBL22728362 | 0.80 | SLC6A4 (0.34) | OPRL1SLC6A4SLC6A2DRD2 | |
| SCHEMBL22728334 | 0.79 | RIPK1 (0.41) | SLC6A4SLC6A2 | |
| SCHEMBL22728339 | 0.75 | IDO1 (0.46) | SLC6A4SLC6A2 | |
| SCHEMBL25926399 | 0.75 | PTGDR2 (0.42) | OPRL1SLC6A4SLC6A2PTGDR2DRD2 | |
| SCHEMBL22719380 | 0.69 | HTR1A (0.39) | OPRL1SLC6A4SLC6A2PTGDR2 | |
| SCHEMBL22728291 | 0.69 | LMNA (0.37) | — | |
| SCHEMBL29453786 | 0.69 | HTR1A (0.39) | OPRL1SLC6A4SLC6A2PTGDR2 | |
| SCHEMBL22719326 | 0.69 | PTGDR2 (0.42) | OPRL1SLC6A4SLC6A2PTGDR2 | |
| SCHEMBL29453732 | 0.69 | PTGDR2 (0.42) | OPRL1SLC6A4SLC6A2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020243027-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | SAGE THERAPEUTICS, INC. (US) | 2020-12-03 | — | — | WO | disclosed |