Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.46 |
| ▸ | TUBB | P07437 | 4/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11290656 | 0.82 | PTGS2 (0.53) | PTGS2HTR2AHTR2CHTR2BCYP3A4 | |
| SCHEMBL28083679 | 0.82 | PTGS2 (0.53) | PTGS2HTR2AHTR2CHTR2BCYP3A4 | |
| SCHEMBL2336218 | 0.81 | PTGS2 (0.57) | PTGS2HTR2AHTR2CHTR2BMAPT | |
| SCHEMBL499116 | 0.80 | GAA (0.61) | PTGS2HTR2AHTR2CHTR2BCYP3A4 | |
| SCHEMBL6845422 | 0.79 | PTGS2 (0.59) | PTGS2HTR2AHTR2CHTR2BCYP3A4 | |
| Hydrochloric Acid SCHEMBL4002124 | 0.78 | GAA (0.59) | PTGS2HTR2AHTR2CHTR2BCYP3A4 | |
| SCHEMBL4683243 | 0.78 | KDM4E (0.55) | PTGS2HTR2AHTR2CHTR2BCYP3A4 | |
| SCHEMBL2399663 | 0.78 | CA2 (0.59) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7046945 | 0.78 | PTGS2 (0.57) | PTGS2HTR2AHTR2CHTR2BCYP3A4 | |
| SCHEMBL9341764 | 0.77 | KMT2A (0.54) | PTGS2HTR2AHTR2CHTR2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9521845-B2 | Beta-lactones as antibacterial agents | LUDWIG-MAXIMILIANS-UNIVERSITÄT-MÜNCHEN (DE) | 2016-12-20 | — | — | US | disclosed |
| US-20140163094-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2014-06-12 | — | — | US | disclosed |
| US-8669283-B2 | Beta-lactones as antibacterial agents | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2014-03-11 | — | — | US | disclosed |
| US-8563598-B2 | — | — | 2013-10-22 | — | — | US | disclosed |
| US-20110196027-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN | 2011-08-11 | — | — | US | disclosed |
| EP-2254574-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | Ludwig-Maximilians-Universität München (DE) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009106211-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2009-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140163094-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | ALG8, PGLS, GLA | PTGS2 1607/4885HTR2A 4854/4885HTR2C 4877/4885 |
| US-20110196027-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | ALG8, PGLS, GLA | PTGS2 1607/4885HTR2A 4854/4885HTR2C 4877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.