Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435863 | 0.84 | MEN1 (0.36) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3990055 | 0.81 | MEN1 (0.66) | MEN1KMT2AALDH1A1TSHRCYP4F2 | |
| SCHEMBL6383219 | 0.81 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1TSHRCYP4F2 | |
| SCHEMBL20211699 | 0.80 | MEN1 (0.53) | MEN1KMT2AALDH1A1TSHRCYP4F2 | |
| SCHEMBL16841345 | 0.79 | MEN1 (0.37) | MEN1KMT2AALDH1A1TSHRCYP4F2 | |
| Ammonia Solution, Strong SCHEMBL20957487 | 0.79 | CYP4F2 (0.44) | MEN1KMT2AALDH1A1TSHRCYP4F2 | |
| SCHEMBL6733638 | 0.78 | MEN1 (0.52) | MEN1KMT2AALDH1A1TSHRCYP4F2 | |
| Ammonia Solution, Strong SCHEMBL376169 | 0.77 | MEN1 (0.50) | MEN1KMT2AALDH1A1TSHRCYP4F2 | |
| SCHEMBL7441186 | 0.76 | MMP8 (0.55) | MEN1KMT2AALDH1A1TSHRMMP8 | |
| SCHEMBL23389053 | 0.76 | MEN1 (0.49) | MEN1KMT2AALDH1A1TSHRCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3744718-A1 | HIGHLY ACTIVE CSF1R INHIBITOR COMPOUND | Adlai Nortye Biopharma Co., Ltd. (CN) | 2020-12-02 | — | — | EP | disclosed |