Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 4/20 | 0.38 |
| ▸ | CTSL | P07711 | 3/20 | 0.38 |
| ▸ | CTSB | P07858 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21384832 | 0.87 | PTPN1 (0.45) | MMP8ALDH1A1RECQLCTSSCTSL | |
| SCHEMBL10904502 | 0.81 | MMP8 (0.50) | MMP8ALDH1A1RECQLPIN1GPR119 | |
| SCHEMBL9712250 | 0.81 | MMP8 (0.58) | MMP8ALDH1A1RECQLPIN1GPR119 | |
| SCHEMBL23699289 | 0.79 | MMP8 (0.57) | MMP8ALDH1A1RECQLPIN1GPR119 | |
| SCHEMBL27993636 | 0.79 | MMP8 (0.57) | MMP8ALDH1A1RECQLPIN1GPR119 | |
| SCHEMBL21247201 | 0.78 | MMP8 (0.56) | MMP8ALDH1A1RECQLPIN1PPID | |
| SCHEMBL19329165 | 0.78 | MMP8 (0.56) | MMP8ALDH1A1RECQLPIN1GPR119 | |
| SCHEMBL7942748 | 0.78 | ALDH1A1 (0.55) | MMP8ALDH1A1RECQLPIN1PPID | |
| SCHEMBL8710582 | 0.77 | MMP8 (0.79) | MMP8ALDH1A1RECQLPIN1PPID | |
| SCHEMBL1492859 | 0.77 | MMP8 (0.65) | MMP8ALDH1A1RECQLPIN1PPID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6066666-A | OPTIONALLY N-SUBSTITUTED 3-MONO- AND DI-SUBSTITUTED 2-PYRROLIDINONES AND THIOLACTAM ANALOGS; TREAT SEIZURES, ANXIETY, AND ENHANCING 4-AMINOBUTYRIC ACID (GABA)-INDUCED CHLORIDE CURRENTS AT GABA RECEPTOR/IONOPHORE COMPLEX | WASHINGTON UNIVERSITY (US) | 2000-05-23 | — | — | US | disclosed |
| US-5776959-A | Anticonvulsant and anxiolytic lactam and thiolactam derivatives | WASHINGTON UNIVERSITY (US) | 1998-07-07 | — | — | US | disclosed |