Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | DAGLA | Q9Y4D2 | 9/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ABHD6 | Q9BV23 | 6/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DAGLB | Q8NCG7 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729683 | 0.97 | SCD5 (0.45) | TP53DAGLAHCRTR1HCRTR2CYP3A4 | |
| SCHEMBL22754864 | 0.84 | GABRA1 (0.46) | TP53DAGLAHCRTR1HCRTR2CYP3A4 | |
| SCHEMBL22729509 | 0.83 | HSP90AA1 (0.46) | TP53HSD11B1SCD5 | |
| SCHEMBL22729693 | 0.81 | CYP2C9 (0.61) | MEN1KMT2ACYP2C9CYP2C19HTR2B | |
| SCHEMBL22729499 | 0.80 | HSP90AA1 (0.49) | SCD5 | |
| SCHEMBL22729723 | 0.80 | CYP2C9 (0.47) | HCRTR1HSD11B1CYP2C9CYP2C19HTR2B | |
| SCHEMBL22729812 | 0.79 | CYP2C9 (0.54) | CYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL22729679 | 0.79 | CYP2C9 (0.46) | SCD5CYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL22729502 | 0.77 | RIPK1 (0.47) | HCRTR1HCRTR2SCD5 | |
| SCHEMBL23116410 | 0.76 | HSP90AA1 (0.52) | TP53HCRTR1HCRTR2HSD11B1SCD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11459325-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-10-04 | — | — | US | disclosed |
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-03-25 | — | — | US | disclosed |
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-03-25 | — | — | US | disclosed |
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | GBA1, GBA2, GALC | TP53 3839/4885DAGLA 292/4885HCRTR1 1114/4885 |
| US-11459325-B2 | Heterocyclic compound | GBA1, GBA2, GALC | TP53 3876/4885DAGLA 284/4885HCRTR1 1069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.