Trimethylammonium

Trimethylammonium

SCHEMBL22734552

CC(Cl)NS(=O)(=O)c1ccc(F)c2nsnc12.CN(C)C

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.37
ALDH1A1 P00352 3/20 0.36
MCOLN3 Q8TDD5 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
HSD17B10 Q99714 1/20 0.36
KDM4E B2RXH2 1/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
HTT P42858 1/20 0.33
NLRP3 Q96P20 1/20 0.33
POLB P06746 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trimethylammonium SCHEMBL22734536 0.85 MAPT (0.38) MAPTALDH1A1MCOLN3CYP1A2CYP3A4
SCHEMBL22734519 0.85 ALDH1A1 (0.37) MAPTALDH1A1MCOLN3CYP1A2CYP3A4
Trimethylammonium SCHEMBL22734668 0.82 NLRP3 (0.33) NLRP3
Trimethylammonium SCHEMBL22734573 0.82 KMT2A (0.37) ALDH1A1KMT2ANLRP3POLB
Hydrochloric Acid SCHEMBL22734555 0.79 ALDH1A1 (0.36) MAPTALDH1A1MCOLN3CYP1A2CYP3A4
SCHEMBL22734518 0.74 TSHR (0.46) MAPTALDH1A1CYP2C9CYP2C19KDM4E
SCHEMBL21976083 0.73 KDM4E (0.47) MAPTALDH1A1MCOLN3KDM4EMAPK1
SCHEMBL22734676 0.72 ALDH1A1 (0.37) MAPTALDH1A1MCOLN3CYP1A2CYP3A4
SCHEMBL16049817 0.72 SMN1; SMN2 (0.34) MAPTALDH1A1MCOLN3CYP1A2CYP3A4
Trimethylammonium SCHEMBL22734514 0.69 RORA (0.46) MAPTALDH1A1MEN1KMT2ANLRP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200386767-A1 Analytical method and apparatus using fingerprints on the basis of types in expression levels of express trace proteins and/or peptides contained in living tissue and/or biological fluid SHINWA CHEMICAL INDUSTRIES LTD. (JP) 2020-12-10 US disclosed