Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.35 |
| ▸ | GLI1 | P08151 | 2/20 | 0.35 |
| ▸ | GLI2 | P10070 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 5/20 | 0.32 |
| ▸ | WEE1 | P30291 | 3/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
| ▸ | PRKCB | P05771 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28430382 | 0.84 | GSK3B (0.36) | PRKCAEGFRROCK2GLI1GLI2 | |
| SCHEMBL22215992 | 0.71 | HSD17B10 (0.52) | PRKCAEGFRMEN1MAPTKMT2A | |
| SCHEMBL9040639 | 0.71 | ALDH1A1 (0.40) | PRKCAEGFRMEN1MAPTKMT2A | |
| SCHEMBL14578493 | 0.69 | CCNE2 (0.31) | PRKCACDK5CDK5R1MEN1PRKD3 | |
| SCHEMBL179246 | 0.69 | CA1 (0.38) | PRKCACDK5CDK5R1MEN1PRKD3 | |
| SCHEMBL19621758 | 0.67 | — | — | |
| SCHEMBL2292542 | 0.67 | TXNRD1 (0.50) | PRKCAEGFRROCK2GLI1GLI2 | |
| SCHEMBL7902933 | 0.66 | CDK5 (0.47) | PRKCAEGFRROCK2GLI1GLI2 | |
| SCHEMBL3766420 | 0.65 | — | — | |
| SCHEMBL2019993 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200381627-A1 | POLYPHENOLS AND POLYAMINO DERIVATIVES IN ORGANIC OPTOELECTRONIC COMPONENTS | HELIATEK GMBH (DE) | 2020-12-03 | — | — | US | disclosed |