Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22743004 | 0.81 | BACE1 (0.39) | KMT2AMEN1UHRF1CYP1A2RAB9A | |
| SCHEMBL22743872 | 0.81 | UHRF1 (0.36) | KMT2AMEN1UHRF1RAB9AGFER | |
| SCHEMBL9098370 | 0.79 | RAB9A (0.43) | ALDH1A1KMT2AMEN1KDM4EGAA | |
| SCHEMBL14852747 | 0.78 | PARP10 (0.42) | ALDH1A1KMT2AMEN1KDM4ECYP1A2 | |
| SCHEMBL22742636 | 0.77 | EHMT2 (0.33) | KMT2AMEN1UHRF1RAB9AGFER | |
| SCHEMBL22717228 | 0.74 | NNMT (0.35) | ALDH1A1KMT2AMEN1KDM4EGAA | |
| SCHEMBL22743496 | 0.74 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1KDM4EGAA | |
| SCHEMBL4119102 | 0.73 | NNMT (0.40) | KMT2AMEN1UHRF1RAB9AGFER | |
| SCHEMBL22742236 | 0.73 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1KDM4EGAA | |
| SCHEMBL20153296 | 0.71 | UHRF1 (0.51) | ALDH1A1KDM4EGAAUHRF1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020243178-A1 | HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS | ANGEX PHARMACEUTICAL, INC. (US) | 2020-12-03 | — | — | WO | disclosed |