Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 13/20 | 0.53 |
| ▸ | NOS3 | P29474 | 11/20 | 0.53 |
| ▸ | NOS2 | P35228 | 11/20 | 0.53 |
| ▸ | KDM1A | O60341 | 7/20 | 0.42 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6643954 | 0.83 | NOS1 (0.77) | NOS1NOS3NOS2 | |
| SCHEMBL22742883 | 0.81 | NOS1 (0.71) | NOS1NOS3NOS2 | |
| SCHEMBL13370534 | 0.77 | NOS1 (0.47) | NOS1NOS3NOS2 | |
| SCHEMBL22717048 | 0.70 | NOS1 (0.40) | NOS1NOS3NOS2 | |
| SCHEMBL22716960 | 0.70 | NOS1 (0.40) | NOS1NOS3NOS2 | |
| SCHEMBL22742306 | 0.67 | NOS1 (0.88) | NOS1NOS3NOS2 | |
| SCHEMBL19698537 | 0.67 | NOS3 (0.36) | NOS1NOS3NOS2KDM1AKDM1B | |
| SCHEMBL6644542 | 0.67 | NOS1 (0.71) | NOS1NOS3NOS2 | |
| SCHEMBL6645211 | 0.65 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL6642292 | 0.65 | NOS1 (0.77) | NOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020243178-A1 | HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS | ANGEX PHARMACEUTICAL, INC. (US) | 2020-12-03 | — | — | WO | disclosed |