Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL741534 | 0.75 | TDP1 (0.34) | TDP1HDAC6HSP90AA1TLR9MAPT | |
| SCHEMBL5086744 | 0.74 | MEN1 (0.41) | TDP1HDAC6MEN1HTTKMT2A | |
| SCHEMBL5083754 | 0.72 | TDP1 (0.35) | TDP1HDAC6MEN1HTTKMT2A | |
| SCHEMBL5084156 | 0.69 | TDP1 (0.36) | TDP1HDAC6MEN1HTTKMT2A | |
| SCHEMBL29851581 | 0.69 | ATM (0.35) | TDP1HDAC6HSD17B10ALDH1A1ALOX15 | |
| SCHEMBL31729517 | 0.68 | POLB (0.46) | TDP1MEN1HTTKMT2AHSP90AA1 | |
| SCHEMBL5011280 | 0.65 | — | — | |
| SCHEMBL647841 | 0.65 | TDP1 (0.40) | TDP1HDAC6MEN1HTTKMT2A | |
| SCHEMBL398096 | 0.65 | ATM (0.35) | TDP1HDAC6LMNASETD7CYP2D6 | |
| SCHEMBL13020966 | 0.64 | TDP1 (0.65) | TDP1HDAC6MEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107312045-B | Preparation method of substituted cyclopentadienyl metallocene compound | 上海化工研究院有限公司 | 2019-12-13 | — | — | CN | disclosed |
| US-20110196103-A1 | PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST | MITSUI CHEMICALS, INC. (US) | 2011-08-11 | — | — | US | disclosed |
| US-7767313-B2 | Polypropylene composite film comprising a metallocene-catalyzed propylene/1-butene random copolymer | MITSUI CHEMICALS, INC. (JP) | 2010-08-03 | — | — | US | disclosed |
| US-7737239-B2 | Propylene copolymer, polypropylene composition and uses thereof, transition metal compound and olefin polymerization catalyst | MITSUI CHEMICALS, INC. (JP) | 2010-06-15 | — | — | US | disclosed |
| US-7728078-B2 | Blend of a polypropylene and a elastomeric copolymer of 60-90 mol % propylene units and 10- 40 mol % of 1-butene units; sheets and films with excellent flexibility and impact resistance as well as sufficient heat resistance and low-temperature heat-sealability | MITSUI CHEMICALS, INC. (JP) | 2010-06-01 | — | — | US | disclosed |
| US-7678934-B2 | Propylene copolymer, polypropylene composition and uses thereof, transition metal compound and olefin polymerization catalyst | MITSUI CHEMICALS, INC. (JP) | 2010-03-16 | — | — | US | disclosed |
| EP-1988104-B1 | Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization | MITSUI CHEMICALS INC (JP) | 2010-03-03 | — | — | EP | disclosed |
| EP-1985637-B1 | Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization | MITSUI CHEMICALS INC (JP) | 2010-03-03 | — | — | EP | disclosed |
| EP-1985638-B1 | Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization | MITSUI CHEMICALS INC (JP) | 2010-02-17 | — | — | EP | disclosed |
| US-20090043050-A1 | PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST | IKENAGA SHIGENOBU | 2009-02-12 | — | — | US | disclosed |
| EP-1169356-B1 | POLYOLEFIN PRODUCTION | ATOFINA RES (BE) | 2004-07-14 | — | — | EP | disclosed |
| US-20040030051-A1 | Polypropylene having low isotacticity and relatively high melting point | BASELL POLYPROPYLEN GMBH (DE) | 2004-02-12 | — | — | US | disclosed |
| US-6515086-B1 | A process for preparing polyolefins having a monomer length of up to C10, which comprises first contacting: (1) a metallocene catalyst component for the preparation of a polyolefin which comprises an isotactic polyolefin or | FINA RESEARCH, S.A. (BE) | 2003-02-04 | — | — | US | disclosed |
| WO-2002038634-A2 | POLYPROPYLENE HAVING LOW ISOTACTICITY AND RELATIVELY HIGH MELTING POINT | BASELL POLYOLEFINE GMBH (DE) | 2002-05-16 | — | — | WO | disclosed |
| CN-1346373-A | Polyolefin production | ATO FINA RES S A (BE) | 2002-04-24 | — | — | CN | disclosed |
| EP-1169356-A1 | POLYOLEFIN PRODUCTION | ATOFINA Research (BE) | 2002-01-09 | — | — | EP | disclosed |
| US-6329478-B1 | SOLUBILITY IN SATURATED HYDROCARBON SOLVENTS | SUMITMO CHEMICAL COMPANY, LIMITED | 2001-12-11 | — | — | US | disclosed |
| WO-2000049029-A1 | POLYOLEFIN PRODUCTION | FINA RESEARCH S.A. (BE) | 2000-08-24 | — | — | WO | disclosed |
| WO-2000049056-A1 | POLYOLEFIN PRODUCTION | ATOFINA RESEARCH (BE) | 2000-08-24 | — | — | WO | disclosed |
| EP-0842939-A1 | TRANSITION METAL COMPLEX, PROCESS FOR THE PREPARATION THEREOF, POLYMERIZATION CATALYST FOR OLEFINS CONTAINING THE COMPLEX, AND PROCESS FOR PRODUCING OLEFIN POLYMERS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-05-20 | — | — | EP | disclosed |