SCHEMBL398096

SCHEMBL398096

CCC1=CC(C(C)(C)C)=CC1=C(c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.35
TDP1 Q9NUW8 2/20 0.34
HTR1A P08908 1/20 0.34
CYP2D6 P10635 1/20 0.34
SCN1A P35498 1/20 0.34
SLC6A3 Q01959 1/20 0.34
SCN5A Q14524 1/20 0.34
SCN2A Q99250 1/20 0.34
SCN3A Q9NY46 1/20 0.34
LMNA P02545 1/20 0.32
SETD7 Q8WTS6 1/20 0.32
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1235846 0.66 CES2 (0.31) TDP1CES2CES1
SCHEMBL2274381 0.65 TDP1 (0.39) ATMTDP1CYP2D6LMNASETD7
SCHEMBL2803982 0.62 TDP1 (0.30) TDP1CYP2D6LMNASETD7
SCHEMBL9226914 0.59 CES1 (0.43) ATMTDP1CYP2D6LMNASETD7
SCHEMBL29851581 0.57 ATM (0.35) ATMTDP1CYP2D6LMNASETD7
SCHEMBL8462267 0.57 CES1 (0.50) TDP1CYP2D6LMNACES2CES1
SCHEMBL31729517 0.56 POLB (0.46) ATMTDP1LMNACES2CES1
SCHEMBL9493195 0.56 RIPK1 (0.44) ATMTDP1CYP2D6LMNACES2
Hydrogen Peroxide SCHEMBL11570368 0.55 GABRA1 (0.50) ATMTDP1
SCHEMBL24060203 0.55 ATM (0.68) ATMCYP2D6LMNACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2275457-B1 Propylene-based polymer composition, and molded products, sheets, films, laminates and non-woven fabrics obtained therefrom MITSUI CHEMICALS INC (JP) 2016-11-23 EP disclosed
US-20160280819-A1 CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, METHOD FOR PRODUCING PROPYLENE-BASED COPOLYMER, PROPYLENE POLYMER, PROPYLENE-BASED POLYMER COMPOSITION, AND USE OF THOSE MITSUI CHEMICALS, INC. (JP) 2016-09-29 US disclosed
US-9382356-B2 Catalyst for olefin polymerization, method for producing olefin polymer, method for producing propylene-based copolymer, propylene polymer, propylene-based polymer composition, and use of those MITSUI CHEMICALS, INC. (JP) 2016-07-05 US disclosed
EP-1860149-B1 PROPYLENE POLYMER COMPOSITION, USE THEREOF, AND PROCESS FOR PRODUCTION OF THERMOPLASTIC POLYMER COMPOSITION MITSUI CHEMICALS INC (JP) 2016-06-15 EP disclosed
US-8802779-B2 Propylene-based polymer composition, use thereof, and method for producing thermoplastic polymer composition MITSUI CHEMICALS, INC. (JP) 2014-08-12 US disclosed
EP-2080784-B1 PROPYLENE RESIN COMPOSITION, METHOD FOR PRODUCING PROPYLENE RESIN COMPOSITION, PROPYLENE POLYMER COMPOSITION, MOLDED BODY MADE OF THE PROPYLENE RESIN COMPOSITION, AND ELECTRIC WIRE MITSUI CHEMICALS INC (JP) 2013-03-06 EP disclosed
US-8101684-B2 Thermoplastic resin composition for sealing solar cell, sheet for sealing solar cell and solar cell MITSUI CHEMICALS, INC. (JP) 2012-01-24 US disclosed
US-7879960-B2 methyl)(phenyl)methylene(3-tert-butyl-5-ethylcyclopentadienyl)(3,6-di-tert-butylfluorenyl)zirconium dichloride a metallocene], methylalumoxane, triisobutylaluminum containing catalyst system for propylene homo or copolymerization MITSUI CHEMICALS, INC. (JP) 2011-02-01 US disclosed
EP-2275457-A2 Propylene polymer, propylene-based polymer composition, and use of these Mitsui Chemicals, Inc. (JP) 2011-01-19 EP disclosed
US-7863368-B2 Propylene resin composition, process for producing propylene resin composition, propylene polymer composition, shaped article produced of the propylene resin composition, and electric wire MITSUI CHEMICALS, INC. (JP) 2011-01-04 US disclosed
US-20100000600-A1 THERMOPLASTIC RESIN COMPOSITION FOR SEALING SOLAR CELL, SHEET FOR SEALING SOLAR CELL AND SOLAR CELL MITSUI CHEMICALS, INC. 2010-01-07 US disclosed
EP-2085420-A1 POLYPROPYLENE RESIN FILM AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2009-08-05 EP disclosed
EP-2080784-A1 PROPYLENE RESIN COMPOSITION, METHOD FOR PRODUCING PROPYLENE RESIN COMPOSITION, PROPYLENE POLYMER COMPOSITION, MOLDED BODY MADE OF THE PROPYLENE RESIN COMPOSITION, AND ELECTRIC WIRE Mitsui Chemicals, Inc. (JP) 2009-07-22 EP disclosed
EP-2048194-A1 THERMOPLASTIC RESIN COMPOSITION FOR SOLAR CELL SEALING, SHEET FOR SOLAR CELL SEALING, AND SOLAR CELL Mitsui Chemicals, Inc. (JP) 2009-04-15 EP disclosed
US-20080220193-A1 Catalyst for olefin polymerization, method for producing olefin polymer, method for producing propylene-based copolymer, propylene polymer, propylene-based polymer composition, and use of those MITSUI CHEMICALS, INC. 2008-09-11 US disclosed
US-20080097055-A1 Process for Producing Propylene Polymer MITSUI CHEMICALS, INC. (JP) 2008-04-24 US disclosed
US-20080085977-A1 Propylene-based polymer composition, use thereof, and method for producing thermpolastic polymer composition MITSUI CHEMICALS, INC. 2008-04-10 US disclosed
EP-1900758-A1 CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, METHOD FOR PRODUCING PROPYLENE COPOLYMER, PROPYLENE POLYMER, PROPYLENE POLYMER COMPOSITION, AND USE OF THOSE Mitsui Chemicals, Inc. (JP) 2008-03-19 EP disclosed
EP-1860149-A1 PROPYLENE POLYMER COMPOSITION, USE THEREOF, AND PROCESS FOR PRODUCTION OF THERMOPLASTIC POLYMER COMPOSITION Mitsui Chemicals, Inc. (JP) 2007-11-28 EP disclosed
EP-1803742-A1 PROCESS FOR PRODUCING PROPYLENE POLYMER Mitsui Chemicals, Inc. (JP) 2007-07-04 EP disclosed