Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3758698 | 0.73 | SLC6A2 (0.45) | ALDH1A1MAPTPKMHPGDHTT | |
| SCHEMBL30321098 | 0.73 | SLC6A2 (0.45) | ALDH1A1MAPTPKMHPGDHTT | |
| SCHEMBL22744059 | 0.73 | SLC6A2 (0.45) | ALDH1A1MAPTPKMHPGDHTT | |
| SCHEMBL22744134 | 0.70 | HDAC8 (0.34) | HDAC8 | |
| SCHEMBL3082231 | 0.69 | — | — | |
| SCHEMBL22031546 | 0.69 | NAPRT (0.39) | L3MBTL1 | |
| SCHEMBL17681988 | 0.69 | P2RX7 (0.35) | — | |
| SCHEMBL17682018 | 0.69 | P2RX7 (0.35) | — | |
| SCHEMBL8765939 | 0.69 | CES2 (0.34) | ALDH1A1MAPTHTTNPSR1L3MBTL1 | |
| SCHEMBL31570465 | 0.66 | TRPM8 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239999-A1 | SMALL MOLECULE INHIBITORS OF NF-kB INDUCING KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2020-12-03 | — | — | WO | disclosed |