Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.55 |
| ▸ | MMP12 | P39900 | 1/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | DVL1 | O14640 | 1/20 | 0.34 |
| ▸ | DVL3 | Q92997 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 3/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.33 |
| ▸ | PPM1D | O15297 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2280948 | 0.90 | PRKCA (0.51) | PRKCAMMP12SCN9ADVL1DVL3 | |
| SCHEMBL392344 | 0.89 | PRKCA (0.55) | PRKCAMMP12SCN9ANR1I2CYP3A4 | |
| SCHEMBL4206539 | 0.89 | PRKCA (0.66) | PRKCAMMP12SCN9ALTA4HNR1I2 | |
| SCHEMBL394439 | 0.85 | PRKCA (0.57) | PRKCAMMP12SCN9ANR1I2CYP3A4 | |
| SCHEMBL4206393 | 0.85 | PRKCA (0.56) | PRKCAMMP12SCN9ANR1I2CYP3A4 | |
| SCHEMBL393733 | 0.84 | PRKCA (0.51) | PRKCAMMP12SCN9ANR1I2CYP3A4 | |
| SCHEMBL2274538 | 0.84 | PRKCA (0.59) | PRKCAMMP12SCN9ALTA4HNR1I2 | |
| SCHEMBL2273255 | 0.81 | PRKCA (0.54) | PRKCAMMP12SCN9ANR1I2EGLN1 | |
| SCHEMBL3089205 | 0.81 | PRKCA (0.66) | PRKCAMMP12SCN9ANR1I2CYP3A4 | |
| SCHEMBL2279944 | 0.81 | PRKCA (0.70) | PRKCAMMP12SCN9ANR1I2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989438-B2 | Therapeutic compounds | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2011-08-02 | — | — | US | disclosed |