Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | CA12 | O43570 | 3/20 | 0.64 |
| ▸ | CA1 | P00915 | 3/20 | 0.64 |
| ▸ | CA2 | P00918 | 3/20 | 0.64 |
| ▸ | CA3 | P07451 | 3/20 | 0.64 |
| ▸ | CA4 | P22748 | 3/20 | 0.64 |
| ▸ | CA6 | P23280 | 3/20 | 0.64 |
| ▸ | CA5A | P35218 | 3/20 | 0.64 |
| ▸ | CA7 | P43166 | 3/20 | 0.64 |
| ▸ | CA9 | Q16790 | 3/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.64 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.64 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.64 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | DPP4 | P27487 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4938529 | 1.00 | KDM4E (0.64) | KDM4EHSD17B10CA12CA1CA2 | |
| SCHEMBL6010547 | 0.87 | KDM4E (0.64) | KDM4EHSD17B10CA12CA1CA2 | |
| SCHEMBL8153863 | 0.86 | KDM4E (0.56) | KDM4EHSD17B10CA12CA1CA2 | |
| SCHEMBL8153860 | 0.86 | KDM4E (0.56) | KDM4EHSD17B10CA12CA1CA2 | |
| SCHEMBL922228 | 0.82 | KDM4E (0.49) | KDM4EHSD17B10CA12CA1CA2 | |
| SCHEMBL922227 | 0.82 | KDM4E (0.49) | KDM4EHSD17B10CA12CA1CA2 | |
| SCHEMBL19900021 | 0.82 | KDM4E (0.49) | KDM4EHSD17B10CA12CA1CA2 | |
| SCHEMBL19538090 | 0.81 | APP (0.68) | KDM4EHSD17B10CA12CA1CA2 | |
| Caffeic Acid SCHEMBL1172850 | 0.80 | KDM4E (0.96) | KDM4EHSD17B10CA12CA1CA2 | |
| Caffeic Acid SCHEMBL1172851 | 0.80 | KDM4E (0.96) | KDM4EHSD17B10CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023152218-A1 | ANTIMICROBIAL SUSCEPTIBILITY | FASTINOV, SA (PT) | 2023-08-17 | — | — | WO | disclosed |
| CN-107636011-B | Isolated peptides from fibrinogen and fragments thereof for use as medicaments, in particular in skin inflammatory diseases | 巴黎笛卡尔大学 | 2021-07-02 | — | — | CN | disclosed |
| WO-2020225322-A1 | ARGININE-BASED ANTIBACTERIAL POLYMERS WITH UCST PROPERTY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2020-11-12 | — | — | WO | disclosed |
| US-20150352136-A1 | NOVEL AMINOGLYCOSIDES AND USES THEREOF IN THE TREATMENT OF GENETIC DISORDERS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2015-12-10 | — | — | US | disclosed |
| US-20150024955-A1 | Methods of Identifying Modulators of Dephosphorylation of Histone Deacetylase | THE J. DAVID GLADSTONE INSTITUTES | 2015-01-22 | — | — | US | disclosed |
| EP-2751128-A2 | CELL-PENETRATING PEPTIDES HAVING A CENTRAL HYDROPHOBIC DOMAIN | Medical Research Council (GB) | 2014-07-09 | — | — | EP | disclosed |
| US-20130312138-A1 | PLANTS WITH INCREASED ACTIVITY OF A STARCH PHOSPHORYLATING ENZYME | BAYER CROPSCIENCE AG (DE) | 2013-11-21 | — | — | US | disclosed |
| WO-2013103780-A1 | COMPOSITIONS AND METHODS TO BOOST ENDOGENOUS ROS PRODUCTION FROM BACTERIA | TRUSTEES OF BOSTON UNIVERSITY (US) | 2013-07-11 | — | — | WO | disclosed |
| WO-2013030569-A2 | PEPTIDES | GAIT MICHAEL JOHN (GB) | 2013-03-07 | — | — | WO | disclosed |
| WO-2012166055-A1 | METHOD FOR DETECTING DISEASE BIOMARKERS | SINGAPORE HEALTH SERVICES PTE. LTD. (SG) | 2012-12-06 | — | — | WO | disclosed |
| WO-2003044042-A1 | SITE SELECTIVE ACYLATION | MODPRO AB (SE) | 2003-05-30 | — | — | WO | disclosed |
| EP-1250353-A2 | P21 DERIVED PEPTIDES CAPABLE OF INHIBITING CDK/CYCLIN COMPLEXES | Cyclacel Limited (GB) | 2002-10-23 | — | — | EP | disclosed |
| WO-2000072004-A9 | METHOD OF DETERMINING THE THREE-DIMENSIONAL SHAPE OF A MACROMOLECULE | UNIV CALIFORNIA (US) | 2002-08-29 | — | — | WO | disclosed |
| WO-2000023092-A9 | CONTULAKIN-G, ANALOGS THEREOF AND USES THEREFOR | COGNETIX INC (US) | 2002-08-22 | — | — | WO | disclosed |
| US-20010014461-A1 | Retentate chromatography and protein chip arrays with applications in biology and medicine | CIPHERGEN BIOSYSTEMS, INC. | 2001-08-16 | — | — | US | disclosed |
| WO-2001040142-A2 | P21 DERIVED PEPTIDES CAPABLE OF INHIBITING CDK/CYCLIN COMPLEXES | CYCLACEL LIMITED (GB) | 2001-06-07 | — | — | WO | disclosed |
| EP-1086122-A1 | PYRAZINONE PROTEASE INHIBITORS | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (US) | 2001-03-28 | — | — | EP | disclosed |
| EP-0990256-A1 | RETENTATE CHROMATOGRAPHY AND PROTEIN CHIP ARRAYS WITH APPLICATIONS IN BIOLOGY AND MEDICINE | Ciphergen Biosystems, Inc. (US) | 2000-04-05 | — | — | EP | disclosed |
| WO-1999064446-A1 | PYRAZINONE PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1999-12-16 | — | — | WO | disclosed |
| WO-1998059360-A1 | RETENTATE CHROMATOGRAPHY AND PROTEIN CHIP ARRAYS WITH APPLICATIONS IN BIOLOGY AND MEDICINE | CIPHERGEN BIOSYSTEMS, INC. (US) | 1998-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150352136-A1 | NOVEL AMINOGLYCOSIDES AND USES THEREOF IN THE TREATMENT OF GENETIC DISORDERS | AARS1, NARS1, GOT1 | KDM4E 3943/4885HSD17B10 1220/4885CA12 4731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.