SCHEMBL2267447

SCHEMBL2267447

C=C[Si](NCC)(c1ccccc1)C(C)CC

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.33
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
TRPA1 O75762 1/20 0.30
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2275369 0.87 ALDH1A1 (0.31) SIGMAR1MEN1KMT2ATAAR1ELANE
SCHEMBL2275031 0.86 SIGMAR1 (0.34) SIGMAR1MEN1KMT2ATAAR1
SCHEMBL2103827 0.73 SIGMAR1 (0.37) SIGMAR1MEN1KMT2ATAAR1TRPA1
SCHEMBL2274648 0.73 SIGMAR1 (0.37) SIGMAR1MEN1KMT2ATAAR1TRPA1
SCHEMBL2271979 0.72 MEN1 (0.31) MEN1KMT2ATRPA1
SCHEMBL2267732 0.72 ALDH1A1 (0.31) SIGMAR1MEN1KMT2ATAAR1
SCHEMBL2272879 0.71 GRIN1 (0.30) MEN1KMT2A
SCHEMBL2269062 0.71 KCNN4 (0.33) SIGMAR1
SCHEMBL2103464 0.71 KCNN4 (0.33) SIGMAR1
SCHEMBL2099899 0.70 SIGMAR1 (0.35) SIGMAR1MEN1KMT2ATAAR1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed