Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 3/20 | 0.44 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28797628 | 0.81 | PTPN22 (0.47) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL3130959 | 0.81 | NR4A1 (0.63) | LDHANR4A1NR4A2NR4A3WDR5 | |
| SCHEMBL3130205 | 0.78 | NR4A1 (0.59) | LDHANR4A1NR4A2NR4A3WDR5 | |
| SCHEMBL31472706 | 0.77 | PTPN22 (0.43) | ALDH1A1KDM4EGAAHSD17B10ERN1 | |
| SCHEMBL28797621 | 0.77 | MAPT (0.44) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL29409566 | 0.77 | ALDH1A1 (0.62) | NR4A1NR4A2NR4A3CDC25BALDH1A1 | |
| SCHEMBL69321 | 0.77 | ALDH1A1 (0.62) | NR4A1NR4A2NR4A3CDC25BALDH1A1 | |
| SCHEMBL28624944 | 0.76 | PTPN22 (0.48) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL17616900 | 0.72 | ALOX5 (0.45) | ACMSDMCL1ALDH1A1KDM4EGAA | |
| Phenanthrene SCHEMBL31651179 | 0.71 | NR4A1 (0.75) | LDHANR4A1NR4A2NR4A3WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220304958-A1 | SMALL MOLECULE INHIBITORS OF A PROTEIN COMPLEX | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-09-29 | — | — | US | disclosed |
| WO-2020247608-A1 | SMALL MOLECULE INHIBITORS OF A PROTEIN COMPLEX | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220304958-A1 | SMALL MOLECULE INHIBITORS OF A PROTEIN COMPLEX | SERBP1, PPHLN1, VCAM1 | LDHA 4482/4885NR4A1 2806/4885NR4A2 2131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.