SCHEMBL3130205

SCHEMBL3130205

O=C(O)c1cccc(C(=O)O)c1C#Cc1cccc2ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.59
NR4A2 P43354 1/20 0.59
NR4A3 Q92570 1/20 0.59
CDC25B P30305 1/20 0.53
WDR5 P61964 1/20 0.47
LDHA P00338 1/20 0.46
CHAT P28329 1/20 0.43
MMP3 P08254 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
ALDH1A1 P00352 3/20 0.42
HPGD P15428 2/20 0.42
MAPT P10636 2/20 0.42
HTT P42858 2/20 0.42
ALOX15 P16050 1/20 0.42
HSP90AA1 P07900 1/20 0.42
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
KDM4E B2RXH2 2/20 0.41
GFER P55789 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3130959 0.90 NR4A1 (0.63) NR4A1NR4A2NR4A3CDC25BWDR5
SCHEMBL28738493 0.85 NR4A1 (0.58) NR4A1NR4A2NR4A3CDC25BWDR5
SCHEMBL22750705 0.78 LDHA (0.49) NR4A1NR4A2NR4A3CDC25BWDR5
SCHEMBL3137844 0.78 HSD17B10 (0.52) NR4A1NR4A2NR4A3CDC25BWDR5
SCHEMBL28979636 0.78 NR4A1 (0.47) NR4A1NR4A2NR4A3CDC25BCHAT
SCHEMBL29798114 0.78 CHAT (0.53) CHATALDH1A1HPGDMAPTHTT
SCHEMBL29661843 0.78 CHAT (0.60) CHATALDH1A1HPGDMAPTHTT
SCHEMBL2776015 0.78 CHAT (0.60) CHATALDH1A1HPGDMAPTHTT
Naphthoic Acid SCHEMBL11742303 0.77 NR4A1 (0.70) NR4A1NR4A2NR4A3CDC25BWDR5
SCHEMBL5667414 0.77 HNF4A (0.54) NR4A1NR4A2NR4A3CDC25BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2344568-B1 ACETYLENIC POLYAMIDE NEXAM CHEMICAL AB (SE) 2017-12-20 EP claimed
CN-115197565-B Semi-crystalline polyamide composition based on short diamines with high glass transition temperature, process for its production and use thereof 阿科玛法国公司 2024-10-11 CN disclosed
CN-115197565-A Semi-crystalline polyamide composition based on short diamines with high glass transition temperature, method for the production thereof and use thereof 阿科玛法国公司 2022-10-18 CN disclosed
CN-110446740-B Semi-crystalline polyamide compositions based on short diamines with high glass transition temperature, method for the production thereof and use thereof 阿科玛法国公司 2022-07-12 CN disclosed
CN-110431169-B Semi-crystalline polyamide composition having a high glass transition temperature and a high melting temperature, method for preparing same and use thereof 阿科玛法国公司 2022-05-17 CN disclosed
CN-108026267-B Semi-crystalline polyamide composition with high glass transition temperature for thermoplastic materials, method for the production thereof and use thereof 阿科玛法国公司 2021-02-02 CN disclosed
CN-107949596-B Semi-crystalline polyamide component with high glass transition temperature for composite materials, method for the production thereof and use thereof 阿科玛法国公司 2021-02-02 CN disclosed
WO-2010036175-A1 MOULDED ARTICLE OBTAINED FROM ACETYLENIC POLYAMIDE NEXAM CHEMICALS (SE) 2010-04-01 WO disclosed