Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 20/20 | 0.71 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23128687 | 0.86 | CYP11B2 (0.72) | CYP11B2CYP11B1 | |
| SCHEMBL21831966 | 0.83 | CYP11B2 (1.00) | CYP11B2CYP11B1 | |
| SCHEMBL21832005 | 0.83 | CYP11B2 (0.83) | CYP11B2CYP11B1 | |
| SCHEMBL21831984 | 0.82 | CYP11B2 (1.00) | CYP11B2CYP11B1 | |
| SCHEMBL21832035 | 0.82 | CYP11B2 (1.00) | CYP11B2CYP11B1 | |
| SCHEMBL21831985 | 0.82 | CYP11B2 (1.00) | CYP11B2CYP11B1 | |
| SCHEMBL23128885 | 0.81 | CYP11B2 (0.77) | CYP11B2CYP11B1 | |
| SCHEMBL21832040 | 0.80 | CYP11B2 (1.00) | CYP11B2CYP11B1 | |
| SCHEMBL21831960 | 0.80 | CYP11B2 (1.00) | CYP11B2CYP11B1 | |
| SCHEMBL21832042 | 0.80 | CYP11B2 (1.00) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10858342-B2 | Bicyclic imidazole derivatives useful for the treatment of renal diseases, cardiovascular diseases and fibrotic diseases | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10858342-B2 | Bicyclic imidazole derivatives useful for the treatment of renal diseases, cardiovascular diseases and fibrotic diseases | REN, AGTR1, AGTR2 | CYP11B2 61/4885CYP11B1 66/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.