SCHEMBL2275330

SCHEMBL2275330

CC(CC(=O)OC(C)C)CC(=O)OC(C)C

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
TSHR P16473 2/20 0.46
MMP1 P03956 1/20 0.41
MMP2 P08253 1/20 0.41
MMP3 P08254 1/20 0.41
MMP9 P14780 1/20 0.41
MMP13 P45452 1/20 0.41
CYP2D6 P10635 1/20 0.37
ALDH1A1 P00352 3/20 0.36
MAPT P10636 2/20 0.36
HCAR2 Q8TDS4 1/20 0.36
PRKCA P17252 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5069246 0.91 TSHR (0.42) LMNATSHRMMP1MMP2MMP3
SCHEMBL22087967 0.87 LMNA (0.42) LMNATSHRMMP1MMP2MMP3
SCHEMBL12224068 0.87 LMNA (0.47) LMNATSHRMMP1MMP2MMP3
SCHEMBL18033443 0.84 LMNA (0.39) LMNATSHRMMP1MMP2MMP3
SCHEMBL18031543 0.84 LMNA (0.39) LMNATSHRMMP1MMP2MMP3
SCHEMBL127431 0.83 MMP1 (0.58) LMNATSHRMMP1MMP2MMP3
SCHEMBL11326360 0.82 LMNA (0.38) LMNATSHRMMP1MMP2MMP3
Ammonia Solution, Strong SCHEMBL8684701 0.81 MMP1 (0.56) LMNATSHRMMP1MMP2MMP3
SCHEMBL6153825 0.81 LMNA (0.45) LMNATSHRMMP1MMP2MMP3
SCHEMBL2251871 0.81 TSHR (0.47) LMNATSHRMMP1MMP2MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1082359-B1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SRL (IT) 2006-07-19 EP claimed
US-6541582-B1 Catalytic polymerization of propylene via magnesium chloride, titanium chloride, and beta-substituted glutarates; stereospecificity; high isotactic index expressed in terms of high xylene insolubility BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2003-04-01 US claimed
CN-1306544-A Catalyst and components for olefin polymerization BARSELL TECH CO B V (NL) 2001-08-01 CN claimed
EP-1082359-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Basell Technology Company B.V. (NL) 2001-03-14 EP claimed
WO-2000055215-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL TECHNOLOGY COMPANY B.V. (NL) 2000-09-21 WO claimed
US-20230257587-A1 FLUORENYL CYANINE DYES BIOTIUM, INC. 2023-08-17 US disclosed
EP-1875961-B1 CAPSULAR FINE PARTICLE COMPRISING OLEFINIC POLYMER MITSUI CHEMICALS INC (JP) 2018-08-29 EP disclosed
CN-104448066-B A kind of many metal olefin polymerization catalysts of support type and preparation method and application 华东理工大学 2017-07-07 CN disclosed
CN-103635494-B Alpha-olefin polymerization method 胜亚诺盟股份有限公司 2016-12-14 CN disclosed
US-9353198-B2 Method for polymerizing alpha-olefin SUNALLOMER LTD. (JP) 2016-05-31 US disclosed
CN-103351443-B A kind of supported olefin polymerization catalyst and preparation method thereof and application EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2016-02-10 CN disclosed
CN-104448066-A Supported multi-metal olefin polymerization catalyst as well as preparation method and application thereof UNIV EAST CHINA SCIENCE & TECH 2015-03-25 CN disclosed
EP-0125911-B1 PROCESS FOR PRODUCTION OF OLEFIN POLYMER OR COPOLYMER MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-09-20 EP disclosed
CN-1034371-A The preparation method of propylene copolymer MITONI PETROCHEMICAL K K (JP) 1989-08-02 CN disclosed
EP-0303704-A1 PROCESS FOR POLYMERIZING ALPHA-OLEFIN MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-02-22 EP disclosed
CN-88101916-A Olefin polymerization process and catalyst therefor 1988-10-26 CN disclosed
EP-0282341-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-09-14 EP disclosed
EP-0276323-A1 PROCESS FOR PREPARING PROPYLENE COPOLYMER MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-08-03 EP disclosed
EP-0261962-A2 Process for producing propylene block copolymer MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1988-03-30 EP disclosed
EP-0086645-B1 CATALYST COMPOSITION AND PROCESS FOR POLYMERIZING OLEFINS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1986-09-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230257587-A1 FLUORENYL CYANINE DYES FPR3, FPR1, TYR LMNA 1223/4885TSHR 3110/4885MMP1 1972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.