Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK1 | Q9BQI3 | 11/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | GPR39 | O43194 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19929868 | 0.70 | JAK2 (0.43) | EIF2AK1MEN1KMT2ALCKBTK | |
| SCHEMBL13845183 | 0.68 | CSF1R (0.41) | EIF2AK1MEN1KMT2ALCKBTK | |
| SCHEMBL13845176 | 0.66 | JAK2 (0.44) | CSF1R | |
| SCHEMBL19930075 | 0.65 | YTHDC1 (0.38) | — | |
| SCHEMBL19929931 | 0.62 | LMNA (0.38) | EIF2AK1LCKBTKCSF1RMAPT | |
| Hydrochloric Acid SCHEMBL11551221 | 0.61 | HDAC3 (0.54) | LCKBTKTAAR1KDM4EALDH1A1 | |
| SCHEMBL4908101 | 0.58 | HPGD (0.44) | MEN1KMT2AKDM4EALDH1A1PLA2G1B | |
| SCHEMBL18669041 | 0.58 | KDM4E (0.43) | EIF2AK1MEN1KMT2ATAAR1KDM4E | |
| SCHEMBL28137002 | 0.58 | CSF1R (0.49) | TAAR1CSF1RKDM4EALDH1A1PLA2G1B | |
| SCHEMBL2570362 | 0.57 | TAAR1 (0.46) | MEN1KMT2ATAAR1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3290420-B1 | PYRIMIDINE PYRROLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND USES THEREOF | UNIV XIAMEN (CN) | 2020-12-09 | — | — | EP | disclosed |