Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 2/20 | 0.54 |
| ▸ | CDK8 | P49336 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.44 |
| ▸ | KDR | P35968 | 6/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 5/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 3/20 | 0.42 |
| ▸ | PLK4 | O00444 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 2/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14009092 | 0.83 | CCNC (0.56) | CCNCCDK8MAPTMAPK14KDR | |
| SCHEMBL20118148 | 0.77 | PARP1 (0.52) | CCNCCDK8MAPTMAPK14KDR | |
| SCHEMBL13300975 | 0.76 | KDR (0.76) | CCNCCDK8MAPK14KDRMEN1 | |
| SCHEMBL22754686 | 0.72 | CCNC (0.50) | CCNCCDK8MAPTMAPK14KDR | |
| SCHEMBL14792981 | 0.72 | PARP1 (0.52) | KDRPARP1MAP3K20CSF1RPDGFRB | |
| SCHEMBL171414 | 0.72 | LOXL2 (0.53) | KDRPARP1CSF1RRIPK1 | |
| SCHEMBL26075639 | 0.71 | TEK (0.50) | MAPK14KDRRAB9ARAF1BRAF | |
| SCHEMBL2642931 | 0.71 | PARP1 (0.50) | MAPK14KDRRAF1EPHX2PARP1 | |
| SCHEMBL24975884 | 0.71 | CCNC (1.00) | CCNCCDK8MAPTMAPK14SAE1 | |
| SCHEMBL169192 | 0.71 | KMT2A (0.54) | MAPK14KDRKMT2APARP1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747433-A1 | COMBINATION OF CELLULAR IMMUNOTHERAPY | Carsgen Therapeutics Co., Ltd. (CN) | 2020-12-09 | — | — | EP | disclosed |