Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.32 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22754889 | 0.94 | MGLL (0.40) | MGLLNPSR1HTTALDH1A1HPGD | |
| SCHEMBL22754875 | 0.93 | MGLL (0.48) | MGLLNPSR1HTTALDH1A1HPGD | |
| SCHEMBL22755127 | 0.87 | MGLL (0.41) | MGLLNPSR1HTTALDH1A1HPGD | |
| SCHEMBL22755300 | 0.87 | MGLL (0.40) | MGLLNPSR1HTTALDH1A1HPGD | |
| SCHEMBL22755345 | 0.80 | ALDH1A1 (0.33) | MGLLNPSR1HTTALDH1A1HPGD | |
| SCHEMBL22755140 | 0.80 | MGLL (0.42) | MGLLNPSR1HTTALDH1A1HPGD | |
| SCHEMBL22755136 | 0.80 | MGLL (0.34) | MGLLNPSR1HTTALDH1A1HPGD | |
| SCHEMBL22755146 | 0.80 | MGLL (0.35) | MGLLNPSR1HTTALDH1A1HPGD | |
| SCHEMBL22755135 | 0.77 | PDE2A (0.33) | MGLLNPSR1HTTALDH1A1HPGD | |
| SCHEMBL22754859 | 0.75 | SPR (0.45) | MGLLNPSR1HTTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |