Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22755344 | 0.92 | MGLL (0.47) | MGLLSLC6A4SLC6A2SLC6A3HSD11B1 | |
| SCHEMBL22729707 | 0.86 | MGLL (0.40) | MGLLKDM4EALOX15MAPK1SLC6A4 | |
| SCHEMBL22755304 | 0.85 | MGLL (0.40) | MGLL | |
| SCHEMBL22755287 | 0.84 | MGLL (0.38) | MGLLHSD11B1 | |
| SCHEMBL22755295 | 0.84 | MGLL (0.35) | MGLLSLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL22755289 | 0.83 | MGLL (0.37) | MGLLDRD2DRD3KCNH2 | |
| SCHEMBL22754986 | 0.83 | MGLL (0.37) | MGLLMAPK1HSD11B1HSD17B10DRD2 | |
| SCHEMBL22754903 | 0.83 | MGLL (0.37) | MGLLPROKR1ALDH1A1HPGDDRD2 | |
| SCHEMBL22754935 | 0.81 | MGLL (0.35) | MGLL | |
| SCHEMBL22755139 | 0.80 | MGLL (0.39) | MGLLKDM4EALOX15MAPK1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |