Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 5/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729674 | 0.87 | MGLL (0.37) | MGLLDRD2DRD3KCNH2MMP2 | |
| SCHEMBL22729742 | 0.73 | MGLL (0.40) | MGLLDRD2SPR | |
| SCHEMBL22729853 | 0.73 | MGLL (0.38) | MGLLDRD2DRD3KCNH2CA2 | |
| SCHEMBL21767827 | 0.71 | CASR (0.50) | — | |
| SCHEMBL22755289 | 0.71 | MGLL (0.37) | MGLLDRD2DRD3KCNH2PDE2A | |
| SCHEMBL22755032 | 0.69 | MGLL (0.40) | MGLLDRD2DRD3KCNH2 | |
| SCHEMBL22755073 | 0.68 | PDE2A (0.37) | MGLLPDE2ASLC6A9 | |
| SCHEMBL23753011 | 0.68 | MGLL (0.73) | MGLL | |
| SCHEMBL23772393 | 0.68 | MGLL (0.73) | MGLL | |
| SCHEMBL22755344 | 0.68 | MGLL (0.47) | MGLLKCNH2SPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |