Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729740 | 0.87 | MGLL (0.41) | MGLLMAPTSMN1; SMN2NPY5RHTT | |
| SCHEMBL29839319 | 0.87 | MGLL (0.41) | MGLLMAPTSMN1; SMN2NPY5RHTT | |
| SCHEMBL22755270 | 0.86 | MGLL (0.43) | MGLLMAPTSMN1; SMN2NPY5RHTT | |
| SCHEMBL22755139 | 0.86 | MGLL (0.39) | MGLLMAPTHTTHSD11B1KDM4E | |
| SCHEMBL22754887 | 0.85 | MAPT (0.40) | MGLLMAPTSMN1; SMN2HTTCCR8 | |
| SCHEMBL22754885 | 0.83 | HCRTR1 (0.35) | MGLLHCRTR1HCRTR2HSD11B1 | |
| SCHEMBL22755031 | 0.80 | MGLL (0.35) | MGLLHSD11B1 | |
| SCHEMBL29839348 | 0.79 | KDM4E (0.35) | MGLLMAPTSMN1; SMN2HTTHCRTR1 | |
| SCHEMBL22729439 | 0.79 | KDM4E (0.35) | MGLLMAPTSMN1; SMN2HTTHCRTR1 | |
| SCHEMBL22754902 | 0.78 | SLC6A2 (0.36) | MGLLMAPTSMN1; SMN2HTTHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |