Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 5/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.35 |
| ▸ | MGLL | Q99685 | 4/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22755282 | 0.89 | DRD3 (0.34) | MGLLSLC6A9HSD11B1SPR | |
| SCHEMBL22729581 | 0.88 | HCRTR1 (0.36) | HCRTR1HCRTR2MGLLSLC6A9HSD11B1 | |
| SCHEMBL29839404 | 0.88 | HCRTR1 (0.36) | HCRTR1HCRTR2MGLLSLC6A9HSD11B1 | |
| SCHEMBL22755031 | 0.88 | MGLL (0.35) | MGLLHSD11B1 | |
| SCHEMBL22755289 | 0.85 | MGLL (0.37) | MGLLSLC6A9 | |
| SCHEMBL22754902 | 0.84 | SLC6A2 (0.36) | HCRTR1HCRTR2MGLLHSD11B1SPR | |
| SCHEMBL22755266 | 0.83 | MGLL (0.41) | HCRTR1HCRTR2MGLLHSD11B1 | |
| SCHEMBL22755326 | 0.83 | MGLL (0.34) | MGLL | |
| SCHEMBL22755344 | 0.81 | MGLL (0.47) | MGLLHSD11B1SPR | |
| SCHEMBL22755217 | 0.81 | MGLL (0.43) | MGLLSLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |