Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22449271 | 0.87 | KIFC1 (0.44) | KDM4EGRIN2CDGAT1MME | |
| SCHEMBL15037185 | 0.87 | KIFC1 (0.44) | KDM4EGRIN2CDGAT1MME | |
| SCHEMBL22448956 | 0.82 | L3MBTL1 (0.45) | LMNARAB9AMMEGCGR | |
| SCHEMBL22384107 | 0.78 | RARB (0.39) | KDM4ENPC1RAB9A | |
| SCHEMBL22449182 | 0.76 | MME (0.36) | KDM4EGAANPC1KMT2ADGAT1 | |
| SCHEMBL22449139 | 0.76 | MME (0.36) | KDM4EGAANPC1KMT2ADGAT1 | |
| SCHEMBL17968745 | 0.76 | KIFC1 (0.43) | KDM4EDGAT1MAPTMMEALDH1A1 | |
| SCHEMBL15037392 | 0.76 | KIFC1 (0.43) | KDM4EDGAT1MAPTMMEALDH1A1 | |
| SCHEMBL17834867 | 0.76 | KIFC1 (0.43) | KDM4EDGAT1MAPTMMEALDH1A1 | |
| SCHEMBL15037133 | 0.76 | KIFC1 (0.43) | KDM4EDGAT1MAPTMMEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008056-B1 | NOVEL GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-12-09 | — | — | EP | disclosed |