Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIFC1 | Q9BW19 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 6/20 | 0.41 |
| ▸ | ACE | P12821 | 4/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 5/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 3/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15037185 | 1.00 | KIFC1 (0.44) | KIFC1MMEACEACE2MCL1 | |
| SCHEMBL15037392 | 0.89 | KIFC1 (0.43) | KIFC1MMEACEACE2MCL1 | |
| SCHEMBL17968745 | 0.89 | KIFC1 (0.43) | KIFC1MMEACEACE2MCL1 | |
| SCHEMBL15037133 | 0.89 | KIFC1 (0.43) | KIFC1MMEACEACE2MCL1 | |
| SCHEMBL17834867 | 0.89 | KIFC1 (0.43) | KIFC1MMEACEACE2MCL1 | |
| SCHEMBL22756167 | 0.87 | KDM4E (0.38) | MMEDGAT1KDM4EGRIN2C | |
| SCHEMBL17459538 | 0.86 | ITGA4 (0.42) | KIFC1MMEACEACE2ITGA4 | |
| SCHEMBL17459539 | 0.86 | ITGA4 (0.42) | KIFC1MMEACEACE2ITGA4 | |
| SCHEMBL22449211 | 0.86 | L3MBTL1 (0.47) | KIFC1MMEACEACE2ITGA4 | |
| SCHEMBL15037055 | 0.86 | L3MBTL1 (0.47) | KIFC1MMEACEACE2ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791112-B1 | CARBOXYLIC ACID DERIVATIVES COMPRISING FOUR CYCLES ACTING AS GLP-1 RECEPTOR MODULATORS FOR THERAPY OF DISEASES SUCH AS DIABETES | CELGENE INT II SÀRL (CH) | 2020-09-23 | — | — | EP | disclosed |