SCHEMBL2275700

SCHEMBL2275700

CCCC1c2ccccc2-c2cccc([Hf](Cl)(Cl)c3cccc4c3C(CCC)c3ccccc3-4)c21

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.37
BCHE P06276 1/20 0.34
ACHE P22303 1/20 0.34
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
PDE10A Q9Y233 1/20 0.31
SLC22A2 O15244 1/20 0.31
SLC22A3 O75751 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
TDO2 P48775 1/20 0.30
GPR3 P46089 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2274491 0.93 ACHE (0.40) HTR2ABCHEACHE
SCHEMBL27638219 0.80 HTR2A (0.40) HTR2ABCHEACHECYP1A2CYP2C19
Hydrochloric Acid SCHEMBL4307264 0.78 ACHE (0.40) HTR2ABCHEACHE
SCHEMBL6720546 0.78 HTR2A (0.36) HTR2A
SCHEMBL2363189 0.77
SCHEMBL1996543 0.76 HTR2A (0.54) HTR2ABCHEACHECYP1A2CYP2C19
SCHEMBL812495 0.75 HTR2A (0.39) HTR2ABCHEACHECYP1A2CYP2C19
SCHEMBL6759445 0.75 HTR2A (0.39) HTR2ABCHEACHECYP1A2CYP2C19
SCHEMBL30638592 0.75 HTR2A (0.39) HTR2ABCHEACHECYP1A2CYP2C19
Hydrochloric Acid SCHEMBL2275702 0.74 HTR2A (0.38) HTR2ABCHEACHECYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11193008-B2 Methods for making polyolefin polymer compositions EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-12-07 US claimed
US-20200056026-A1 Methods for Making Polyolefin Polymer Compositions EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-02-20 US claimed
WO-2018191000-A1 METHODS FOR MAKING POLYOLEFIN POLYMER COMPOSITIONS EXXONMOBIL CHEMICL PATENTS INC. (US) 2018-10-18 WO claimed
US-20250353944-A1 POLYETHYLENE COMPOSITIONS AND RELATED BICOMPONENT FIBERS, NONWOVEN FABRICS, AND METHODS EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-11-20 US disclosed
EP-4536718-A1 POLYETHYLENE COMPOSITIONS AND RELATED BICOMPONENT FIBERS, NONWOVEN FABRICS, AND METHODS ExxonMobil Chemical Patents Inc. (US) 2025-04-16 EP disclosed
WO-2023244899-A1 POLYETHYLENE COMPOSITIONS AND RELATED BICOMPONENT FIBERS, NONWOVEN FABRICS, AND METHODS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-12-21 WO disclosed
US-11629245-B2 Polyethylene compositions, wire and cables, and methods for making the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-04-18 US disclosed
US-11193008-B2 Methods for making polyolefin polymer compositions EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-12-07 US disclosed
US-20210309842-A1 Polyethylene Compositions, Wire and Cables, and Methods for Making the Same EXXONMOBIL CHEMICAL PATENTS INC (US) 2021-10-07 US disclosed
EP-3814390-A2 POLYETHYLENE COMPOSITIONS, WIRES AND CABLES, AND METHODS FOR MAKING THE SAME ExxonMobil Chemical Patents Inc. (US) 2021-05-05 EP disclosed
US-20200056026-A1 Methods for Making Polyolefin Polymer Compositions EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-02-20 US disclosed
US-7179876-B2 Such as bis(propylcyclopentadienyl) hafnium dichloride, reacting ethylene and a comonomer at given ethylene partial pressure range, and extruding into a film of given secant modulus, dart impact strength UNIVATION TECHNOLOGIES, LLC (US) 2007-02-20 US disclosed
US-7172816-B2 High tear films from hafnocene catalyzed polyethylenes UNIVATION TECHNOLOGIES, LLC (US) 2007-02-06 US disclosed
EP-1694502-A1 HIGH TEAR FILMS FROM HAFNOCENE CATALYZED POLYETHYLENES Univation Technologies, LLC (US) 2006-08-30 EP disclosed
US-20050215716-A1 Such as bis(propylcyclopentadienyl) hafnium dichloride, film of given secant modulus, dart impact strength SZUL JOHN F 2005-09-29 US disclosed
US-6936675-B2 metallocene is represented by the formula: CpHfX2, wherein each X is independently selected from the group consisting of fluorine, chlorine, iodine, bromine, and Cp selected from the fluorene, cyclopentadienyl, indenyl; high impact strength UNIVATION TECHNOLOGIES, LLC (US) 2005-08-30 US disclosed
US-20050171283-A1 Such as bis(propylcyclopentadienyl) hafnium dichloride, reacting ethylene and a comonomer at given ethylene partial pressure range, and extruding into a film of given secant modulus, dart impact strength EXXONMOBIL CHEMICAL PATENTS INC. 2005-08-04 US disclosed
WO-2005061225-A1 HIGH TEAR FILMS FROM HAFNOCENE CATALYZED POLYETHYLENES UNIVATION TECHNOLOGIES, LLC. (US) 2005-07-07 WO disclosed
US-20050058847-A1 metallocene is represented by the formula: CpHfX2, wherein each X is independently selected from the group consisting of fluorine, chlorine, iodine, bromine, and Cp selected from the fluorene, cyclopentadienyl, indenyl; high impact strength UNIVATION TECHNOLOGIES, LLC 2005-03-17 US disclosed
US-6242545-B1 POLYMERIZING OLEFIN(S) IN THE PRESENCE OF A HAFNIUM METALLOCENE CATALYST COMPOUND HAVING A CYCLOPENTADIENYL LIGAND OR DERIVATIVE WITH AT LEAST ONE LINEAR OR ISO ALKYL GROUP ACTIVATOR UNIVATION TECHNOLOGIES 2001-06-05 US disclosed