SCHEMBL6720546

SCHEMBL6720546

C=CCC1c2ccccc2-c2cccc([Hf](Cl)(Cl)c3cccc4c3C(CC=C)c3ccccc3-4)c21

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2275700 0.78 HTR2A (0.37) HTR2A
SCHEMBL17186645 0.77 HTR2A (0.39) HTR2A
SCHEMBL10774990 0.77 HTR2A (0.43) HTR2A
SCHEMBL252162 0.77 HTR2A (0.52) HTR2A
SCHEMBL8169417 0.77 HTR2A (0.36) HTR2A
SCHEMBL6300785 0.77 HTR2A (0.36) HTR2A
SCHEMBL2274491 0.77 ACHE (0.40) HTR2A
SCHEMBL8612084 0.76 HTR2A (0.38) HTR2A
Hydrochloric Acid SCHEMBL8169416 0.76 HTR2A (0.38) HTR2A
SCHEMBL300454 0.76 GABRA1 (0.45) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6746981-B2 OLEFIN POLYMERIZATION CATALYSTS WITH PRODUCTIVITY WHEN FRESH OF >/= 18,000 GRAMS OF POLYETHYLENE PER GRAM OF CATALYST IN ONE HOUR, AND A SPECIFIC SURFACE AREA OF </= 20 M2/G ALBEMARLE CORPORATION 2004-06-08 US disclosed
US-6730758-B2 ADDITION POLYMERIZATION OF ALPHA-OLEFIN HYDROCARBON IN PRESENCE OF SELF-SUPPORTED VINYLOLEFIN-PREPOLYMERIZED CATALYST ALBEMARLE CORPORATION 2004-05-04 US disclosed
EP-1037931-B1 CATALYST COMPOSITIONS OF ENHANCED PRODUCTIVITY ALBEMARLE CORP (US) 2004-02-04 EP disclosed
US-6677265-B1 THE METALLOCENE USED AS THE FEED HAVING IN THE MOLECULE AT LEAST ONE POLYMERIZABLE OLEFINIC SUBSTITUENT ALBEMARLE CORPORATION 2004-01-13 US disclosed
US-20030191254-A1 PARTICULATE GROUP 4 METALLOCENE-ALUMINOXANE CATALYST COMPOSITIONS DEVOID OF PREFORMED SUPPORT, AND THEIR PREPARATION AND THEIR USE ALBEMARLE CORPORATION 2003-10-09 US disclosed
US-20030105253-A1 Particulate group 4 metallocene-aluminoxane catalyst compositions devoid of preformed support, and their preparation and their use ALBEMARLE CORPORATION 2003-06-05 US disclosed
US-6551955-B1 Olefin polymerization catalysts; efficiency ALBEMARLE CORPORATION 2003-04-22 US disclosed
US-6521728-B1 Particulate group 4 metallocene-aluminoxane catalyst compositions devoid of preformed support, and their preparation and their use ALBEMARLE CORPORATION 2003-02-18 US disclosed
WO-2001098380-A2 PARTICULATE GROUP 4 METALLOCENE-ALUMINOXANE CATALYST COMPOSITIONS DEVOID OF PREFORMED SUPPORT, AND THEIR PREPARATION AND THEIR USE ALBEMARLE CORPORATION (US) 2001-12-27 WO disclosed
US-6294496-B1 VERY HIGH PRODUCTIVITIES; PREPOLYMERIZING VINYLOLEFIN WITH A GROUP 4 METALLOCENE-ALUMINOXANE SOLUTION ALBEMARLE CORPORATION 2001-09-25 US disclosed
EP-1037931-A1 CATALYST COMPOSITIONS OF ENHANCED PRODUCTIVITY ALBEMARLE CORPORATION (US) 2000-09-27 EP disclosed
WO-1999029738-A1 CATALYST COMPOSITIONS OF ENHANCED PRODUCTIVITY ALBEMARLE CORPORATION (US) 1999-06-17 WO disclosed