Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | PGK2 | P07205 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22757320 | 0.87 | ADORA3 (0.44) | ALDH1A1LMNAADORA3ADORA1ADORA2A | |
| SCHEMBL22750565 | 0.86 | PGK1 (0.51) | ADORA3ADORA1ADORA2AADORA2BPGK1 | |
| SCHEMBL22757388 | 0.83 | PI4KA (0.53) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL22757421 | 0.81 | ADORA3 (0.55) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL22757435 | 0.79 | SLC29A1 (0.42) | ADORA3ADORA1ADORA2AADORA2BPGK1 | |
| SCHEMBL22757505 | 0.79 | ADORA3 (0.56) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL22757467 | 0.78 | ALDH1A1 (0.43) | ALDH1A1LMNATDP1ADORA2A | |
| SCHEMBL22757494 | 0.76 | ADORA3 (0.58) | ALDH1A1LMNAADORA3ADORA1ADORA2A | |
| SCHEMBL22750530 | 0.76 | ADORA3 (0.58) | ALDH1A1LMNAADORA3ADORA1ADORA2A | |
| SCHEMBL22757426 | 0.75 | ADORA3 (0.51) | ADORA3ADORA1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247546-A1 | ADENOSINE ANALOGS FOR THE TREATMENT OF DISEASE | BIOINTERVENE, INC. (US) | 2020-12-10 | — | — | WO | disclosed |