Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22757426 | 0.85 | ADORA3 (0.51) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL22757515 | 0.85 | ADORA3 (0.51) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL22757467 | 0.85 | ALDH1A1 (0.43) | ADORA2ACYP1A2MAPK1 | |
| SCHEMBL22750565 | 0.85 | PGK1 (0.51) | ADORA2AADORA3ADORA1PGK1PGK2 | |
| SCHEMBL22757415 | 0.79 | PI4KA (0.47) | ADORA2AADORA3ADORA1PGK1PGK2 | |
| SCHEMBL22750530 | 0.78 | ADORA3 (0.58) | ADORA2AADORA3ADORA1ADORA2BMAPK1 | |
| SCHEMBL22757494 | 0.78 | ADORA3 (0.58) | ADORA2AADORA3ADORA1ADORA2BMAPK1 | |
| SCHEMBL22757320 | 0.74 | ADORA3 (0.44) | ADORA2AADORA3ADORA1ADORA2BMAPK1 | |
| SCHEMBL22757424 | 0.74 | ADORA3 (0.53) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL22757451 | 0.72 | ADORA3 (0.41) | ADORA2AADORA3ADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247546-A1 | ADENOSINE ANALOGS FOR THE TREATMENT OF DISEASE | BIOINTERVENE, INC. (US) | 2020-12-10 | — | — | WO | disclosed |