SCHEMBL22758447

SCHEMBL22758447

Cc1ccc2c(c1)sc1ccoc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.39
MCL1 Q07820 1/20 0.39
MAPT P10636 6/20 0.35
RAB9A P51151 6/20 0.35
NPC1 O15118 5/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
NPSR1 Q6W5P4 2/20 0.35
PPARG P37231 1/20 0.35
NR2E3 Q9Y5X4 1/20 0.35
NCOR2 Q9Y618 1/20 0.35
LMNA P02545 3/20 0.34
KDM4E B2RXH2 2/20 0.34
GAA P10253 3/20 0.34
CYP1A2 P05177 2/20 0.33
CYP2A6 P11509 2/20 0.33
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC2 Q92769 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL812518 0.77 BCL2L1 (0.50) BCL2L1MCL1MAPTRAB9ANPC1
SCHEMBL12109032 0.73 BCL2L1 (0.47) BCL2L1MCL1MAPTRAB9ANPC1
SCHEMBL12797457 0.73 BCL2L1 (0.47) BCL2L1MCL1MAPTRAB9ANPC1
SCHEMBL12797460 0.73 BCL2L1 (0.47) BCL2L1MCL1MAPTRAB9ANPC1
SCHEMBL11863869 0.72 GPR3 (0.54) MCL1MAPTRAB9ANPC1SMN1; SMN2
SCHEMBL15834803 0.72 GPR3 (0.30)
SCHEMBL12796856 0.71 BCL2L1 (0.46) BCL2L1MCL1MAPTRAB9ANPC1
SCHEMBL10068340 0.70 BCL2L1 (0.44) BCL2L1MCL1MAPTRAB9ANPC1
SCHEMBL10133862 0.70 BCL2L1 (0.44) BCL2L1MCL1MAPTRAB9ANPC1
SCHEMBL13971125 0.70 BCL2L1 (0.49) BCL2L1MCL1MAPTRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11152578-B2 Sulfonium salts of DNTT and related compounds as soluble photocleavable precursors for organic semiconductors for use in organic field-effect transistors CLAP CO., LTD. (KR) 2021-10-19 US disclosed
US-20200388772-A1 SULFONIUM SALTS OF DNTT AND RELATED COMPOUNDS AS SOLUBLE PHOTOCLEAVABLE PRECURSORS FOR ORGANIC SEMICONDUCTORS FOR USE IN ORGANIC FIELD-EFFECT TRANSISTORS CLAP CO., LTD. (KR) 2020-12-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200388772-A1 SULFONIUM SALTS OF DNTT AND RELATED COMPOUNDS AS SOLUBLE PHOTOCLEAVABLE PRECURSORS FOR ORGANIC SEMICONDUCTORS FOR USE IN ORGANIC FIELD-EFFECT TRANSISTORS DNTT, TST, SULT1A1 BCL2L1 3259/4885MCL1 2876/4885MAPT 158/4885
US-11152578-B2 Sulfonium salts of DNTT and related compounds as soluble photocleavable precursors for organic semiconductors for use in organic field-effect transistors DNTT, TST, SULT1A1 BCL2L1 3259/4885MCL1 2876/4885MAPT 158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.