SCHEMBL22758588

SCHEMBL22758588

COC(=O)[C@@H](N)C[C@@H]1CCCNC1=O

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.37
CCR2 P41597 3/20 0.36
CTSL P07711 2/20 0.35
CTSB P07858 2/20 0.35
CTSS P25774 2/20 0.35
HSD17B10 Q99714 1/20 0.35
ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24113153 1.00 L3MBTL1 (0.37) L3MBTL1CCR2CTSLCTSBCTSS
SCHEMBL24755293 1.00 L3MBTL1 (0.37) L3MBTL1CCR2CTSLCTSBCTSS
SCHEMBL26601377 1.00 L3MBTL1 (0.37) L3MBTL1CCR2CTSLCTSBCTSS
Hydrochloric Acid SCHEMBL26601380 0.99 L3MBTL1 (0.36) L3MBTL1CCR2CTSLCTSBCTSS
Hydrochloric Acid SCHEMBL26601364 0.99 L3MBTL1 (0.36) L3MBTL1CCR2CTSLCTSBCTSS
Hydrochloric Acid SCHEMBL30377284 0.99 L3MBTL1 (0.36) L3MBTL1CCR2CTSLCTSBCTSS
Hydrochloric Acid SCHEMBL30623995 0.92 POLB (0.36) L3MBTL1CCR2HSD17B10
SCHEMBL14838021 0.91 CTSL (0.38) CTSLCTSB
SCHEMBL15985641 0.91 CTSL (0.38) CTSLCTSB
SCHEMBL23754143 0.91 CTSL (0.38) CTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260116857-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOFS PARDES BIOSCIENCES INC (US) 2026-04-30 US disclosed
US-20250195495-A1 RNA Virus Inhibitor Compounds and Uses Thereof THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2025-06-19 US disclosed
US-12186309-B2 RNA virus inhibitor compounds and uses thereof THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2025-01-07 US disclosed
US-12145911-B2 Inhibitors of cysteine proteases and methods of use thereof Pardes Biosciences, Inc. (US) 2024-11-19 US disclosed
US-20240277795-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF PARDES BIOSCIENCES INC (US) 2024-08-22 US disclosed
US-20240270693-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. (US) 2024-08-15 US disclosed
US-20240270721-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. 2024-08-15 US disclosed
EP-4387980-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. (US) 2024-06-26 EP disclosed
US-11952365-B2 Anti-viral compounds ALIGOS THERAPEUTICS, INC. (US) 2024-04-09 US disclosed
CN-116685576-A Cysteine protease inhibitors and methods of use thereof 美商帕迪斯生物科学公司 2023-09-01 CN disclosed
US-20220324844-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. 2022-10-13 US disclosed
US-20220162194-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. 2022-05-26 US disclosed
US-20220162194-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. 2022-05-26 US disclosed
US-11312704-B2 Inhibitors of cysteine proteases and methods of use thereof Pardes Biosciences, Inc. (US) 2022-04-26 US disclosed
US-11312704-B2 Inhibitors of cysteine proteases and methods of use thereof Pardes Biosciences, Inc. (US) 2022-04-26 US disclosed
WO-2021252644-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. (US) 2021-12-16 WO disclosed
US-20210355111-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. 2021-11-18 US disclosed
US-11174231-B1 Inhibitors of cysteine proteases and methods of use thereof Pardes Biosciences, Inc. (US) 2021-11-16 US disclosed
US-11124497-B1 Inhibitors of cysteine proteases and methods of use thereof Pardes Biosciences, Inc. (US) 2021-09-21 US disclosed
WO-2020247665-A1 PEPTIDOMIMETICS FOR THE TREATMENT OF CORONAVIRUS AND PICORNAVIRUS INFECTIONS EMORY UNIVERSITY (US) 2020-12-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11952365-B2 Anti-viral compounds EIF2AK2, ZC3HAV1, HAVCR2 L3MBTL1 3223/4885CCR2 1926/4885CTSL 1088/4885
US-20260116857-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOFS CTRC, CTRL, CTSL L3MBTL1 358/4885CCR2 465/4885CTSL 3/4885
US-11312704-B2 Inhibitors of cysteine proteases and methods of use thereof CTSV, CTRL, CTSL L3MBTL1 605/4885CCR2 1005/4885CTSL 3/4885
US-20220162194-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF CTSV, CTRL, CTSL L3MBTL1 605/4885CCR2 1005/4885CTSL 3/4885
US-20210355111-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF CTRL, CTSV, CTSL L3MBTL1 223/4885CCR2 1295/4885CTSL 3/4885
US-11124497-B1 Inhibitors of cysteine proteases and methods of use thereof CTRL, CTSV, CTSL L3MBTL1 237/4885CCR2 1082/4885CTSL 3/4885
US-20240270693-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF CTRL, CTSV, CTSL L3MBTL1 223/4885CCR2 1295/4885CTSL 3/4885
US-11174231-B1 Inhibitors of cysteine proteases and methods of use thereof CTRL, CTSV, CTSL L3MBTL1 223/4885CCR2 1295/4885CTSL 3/4885
US-20250195495-A1 RNA Virus Inhibitor Compounds and Uses Thereof NSUN3, EIF2AK2, NSUN2 L3MBTL1 747/4885CCR2 2411/4885CTSL 1617/4885
US-20240277795-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF CTRL, CPN1, CTSL L3MBTL1 239/4885CCR2 1735/4885CTSL 3/4885
US-20240270721-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF CTSV, CTRL, CTSL L3MBTL1 605/4885CCR2 1005/4885CTSL 3/4885
US-12186309-B2 RNA virus inhibitor compounds and uses thereof NSUN3, EIF2AK2, NSUN2 L3MBTL1 747/4885CCR2 2411/4885CTSL 1617/4885
US-20220324844-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF CTSV, CTRL, CTSL L3MBTL1 605/4885CCR2 1005/4885CTSL 3/4885
US-12145911-B2 Inhibitors of cysteine proteases and methods of use thereof CTRL, CTSV, CTSL L3MBTL1 223/4885CCR2 1295/4885CTSL 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.