Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22760338 | 0.93 | HPGD (0.42) | HPGDALDH1A1MEN1KMT2AHTT | |
| SCHEMBL22760060 | 0.87 | NOTUM (0.40) | HPGDALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL22760109 | 0.86 | HPGD (0.48) | HPGDALDH1A1MEN1KMT2AHTT | |
| SCHEMBL22747885 | 0.85 | HPGD (0.45) | HPGDALDH1A1MEN1KMT2AHTT | |
| SCHEMBL22748339 | 0.85 | HPGD (0.42) | HPGDALDH1A1MEN1KMT2AHTT | |
| SCHEMBL22747837 | 0.83 | ALDH1A1 (0.45) | HPGDALDH1A1MEN1KMT2AHTT | |
| SCHEMBL22760214 | 0.83 | MAPT (0.42) | HPGDALDH1A1MAPK1ELANEMAPT | |
| SCHEMBL22760342 | 0.81 | HPGD (0.45) | HPGDALDH1A1MEN1KMT2AHTT | |
| SCHEMBL22760184 | 0.80 | MAPK8 (0.48) | HPGDALDH1A1MAPTGAA | |
| SCHEMBL22760133 | 0.79 | MAPK8 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |