Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 16/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAT2A | P31153 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22760116 | 0.86 | ALDH1A1 (0.47) | ALDH1A1GAAMAPTMAT2AHPGD | |
| SCHEMBL22747837 | 0.85 | ALDH1A1 (0.45) | ALDH1A1GAAMAPTMAT2AHPGD | |
| SCHEMBL22748254 | 0.85 | MAT2A (0.46) | MAPK8MAPK9MAT2A | |
| SCHEMBL22748257 | 0.84 | MAPT (0.48) | MAPK8MAPK9ALDH1A1GAAMAPT | |
| SCHEMBL22760109 | 0.82 | HPGD (0.48) | MAPK8ALDH1A1GAAMAPTHPGD | |
| SCHEMBL22760115 | 0.80 | MAPT (0.46) | ALDH1A1GAAMAPTHPGD | |
| SCHEMBL22760089 | 0.80 | HPGD (0.44) | ALDH1A1GAAMAPTHPGD | |
| SCHEMBL22760359 | 0.78 | ALDH1A1 (0.46) | ALDH1A1GAAMAPTHPGD | |
| SCHEMBL22760172 | 0.78 | MAPT (0.47) | ALDH1A1GAAMAPTMAT2AHPGD | |
| SCHEMBL19831035 | 0.78 | MAPK8 (0.51) | MAPK8MAPK9ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |