SCHEMBL2276014

SCHEMBL2276014

CC(C(=O)O)N(C1CCCCC1)C1CCNCC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 6/20 0.38
SLC6A4 P31645 6/20 0.38
FDPS P14324 1/20 0.38
SLC6A3 Q01959 2/20 0.37
KCNH2 Q12809 1/20 0.37
EPHX1 P07099 1/20 0.37
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
GABRA1 P14867 1/20 0.35
TSHR P16473 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35
GABRA5 P31644 1/20 0.35
GABRA3 P34903 1/20 0.35
GABRA2 P47869 1/20 0.35
GABRB2 P47870 1/20 0.35
GABRA4 P48169 1/20 0.35
GABRE P78334 1/20 0.35
PMP22 Q01453 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL601669 0.89 FDPS (0.45) FDPSTSHRADH1BADH1CADH1A
SCHEMBL1468324 0.89 FDPS (0.45) FDPSTSHRADH1BADH1CADH1A
SCHEMBL601670 0.89 FDPS (0.45) FDPSTSHRADH1BADH1CADH1A
SCHEMBL16149273 0.85 FDPS (0.39) FDPSADH1BADH1CADH1A
SCHEMBL16149274 0.85 FDPS (0.39) FDPSADH1BADH1CADH1A
SCHEMBL158232 0.72 ALDH1A1 (0.40) TSHRADH1BADH1CADH1A
SCHEMBL555055 0.72 ALDH1A1 (0.40) TSHRADH1BADH1CADH1A
SCHEMBL2275673 0.71 TSHR (0.55) SLC6A2SLC6A4SLC6A3KCNH2EPHX1
SCHEMBL23042510 0.71 NOS2 (0.37) SLC6A2SLC6A4SLC6A3KCNH2GABRP
SCHEMBL829497 0.71 NOS2 (0.37) SLC6A2SLC6A4SLC6A3KCNH2GABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7989634-B2 Melanocortin receptor agonists LG LIFE SCIENCES LTD. (KR) 2011-08-02 US disclosed
US-20070129346-A1 Melanocortin receptor agonists LG LIFE SCIENCES LTD. (KR) 2007-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129346-A1 Melanocortin receptor agonists MC1R, MC3R, MC5R SLC6A2 272/4885SLC6A4 386/4885FDPS 4798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.