SCHEMBL158232

SCHEMBL158232

C[C@@H](C(=O)O)N(C)C1CCCCC1

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
ADH1C P00326 2/20 0.39
ADH1A P07327 2/20 0.39
ADH1B P00325 1/20 0.39
ATM Q13315 1/20 0.38
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL555055 1.00 ALDH1A1 (0.40) ALDH1A1ADH1CADH1AADH1BATM
SCHEMBL200643 0.98 ALDH1A1 (0.37) ALDH1A1ADH1CADH1AADH1BATM
SCHEMBL200642 0.98 ALDH1A1 (0.37) ALDH1A1ADH1CADH1AADH1BATM
Hydrochloric Acid SCHEMBL5204062 0.96 ALDH1A1 (0.36) ALDH1A1ADH1CADH1AADH1BATM
SCHEMBL23275897 0.89 TP53 (0.33)
SCHEMBL23275898 0.89 TP53 (0.33)
SCHEMBL7269871 0.88 ALDH1A1 (0.33) ALDH1A1ADH1CADH1AADH1BATM
SCHEMBL601670 0.81 FDPS (0.45) ALDH1A1ADH1CADH1AADH1BTSHR
SCHEMBL11174606 0.81 ALDH1A1 (0.41) ALDH1A1ADH1CADH1AADH1BATM
SCHEMBL1468324 0.81 FDPS (0.45) ALDH1A1ADH1CADH1AADH1BTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1938 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240317803-A1 BCL9 PEPTIDES AND VARIANTS THEREOF WNTRX PHARMACEUTICALS INC. 2024-09-26 US claimed
US-20090215895-A1 Therapeutic and carrier molecules PEPLIN BIOLIPIDS PTY LTD (AU) 2009-08-27 US claimed
EP-1006122-B1 PHENETHYLAMINE DERIVATIVES CHUGAI PHARMACEUTICAL CO LTD (JP) 2008-12-03 EP claimed
EP-1718602-A4 THERAPEUTIC AND CARRIER MOLECULES PEPLIN BIOLIPIDS PTY LTD (AU) 2007-12-12 EP claimed
US-7256172-B1 Method of treatment and agents useful for same THE UNIVERSITY OF MELBOURNE (AU) 2007-08-14 US claimed
EP-1718602-A1 THERAPEUTIC AND CARRIER MOLECULES Peplin Biolipids Pty Ltd. (AU) 2006-11-08 EP claimed
WO-2005073164-A1 THERAPEUTIC AND CARRIER MOLECULES PEPLIN BIOLIPIDS PTY LTD (AU) 2005-08-11 WO claimed
EP-0699074-B1 THROMBIN INHIBITORS MERCK & CO INC (US) 2002-11-13 EP claimed
US-6255285-B1 GASTROINTESTINAL DISORDERS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2001-07-03 US claimed
EP-1006122-A1 PHENETHYLAMINE DERIVATIVES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2000-06-07 EP claimed
EP-0699074-A4 THROMBIN INHIBITORS MERCK & CO INC (US) 1998-03-11 EP claimed
US-5672582-A ANTICOAGULANTS; 4-SUBSTITUTED CYCLOHEXYLAMINE DERIVATIVES MERCK & CO., INC. (US) 1997-09-30 US claimed
EP-0699074-A1 THROMBIN INHIBITORS MERCK & CO. INC. (US) 1996-03-06 EP claimed
WO-1994025051-A1 THROMBIN INHIBITORS MERCK & CO., INC. (US) 1994-11-10 WO claimed
US-20260140060-A1 COLORIMETRIC DETECTION OF A VIRAL INFECTION RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2026-05-21 US disclosed
US-20260124281-A1 FORMULATIONS COMPRISING ACID-NEUTRALIZING POLYMER FOR ORAL ADMINISTRATION OF PARATHYROID HORMONE ENTERA BIO LTD. (IL) 2026-05-07 US disclosed
EP-4731266-A1 NANOPARTICLE COMPOSITIONS ASSOCIATED WITH PEPTIDES The Regents of the University of Michigan (US) 2026-04-29 EP disclosed
WO-1994025051-A1 THROMBIN INHIBITORS MERCK & CO., INC. (US) 1994-11-10 WO disclosed
WO-1994011388-A1 SUPPORT FOR THE SYNTHESIS OF MODULAR POLYMERS CHIRON MIMOTOPES PTY. LTD. (AU) 1994-05-26 WO disclosed
WO-1994003483-A1 ENDOTHELIN RECEPTOR-BINDING COMPOUNDS CHIRON CORPORATION (US) 1994-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215895-A1 Therapeutic and carrier molecules PHKG1, PHKG2, DGKB ALDH1A1 3631/4885ADH1C 1775/4885ADH1A 3729/4885
US-20240317803-A1 BCL9 PEPTIDES AND VARIANTS THEREOF BCL9, BCL9L, BCL3 ALDH1A1 4768/4885ADH1C 3527/4885ADH1A 4576/4885
US-20260124281-A1 FORMULATIONS COMPRISING ACID-NEUTRALIZING POLYMER FOR ORAL ADMINISTRATION OF PARATHYROID HORMONE PTH1R, FGF23, PTMS ALDH1A1 2763/4885ADH1C 753/4885ADH1A 1516/4885
US-20260140060-A1 COLORIMETRIC DETECTION OF A VIRAL INFECTION CTSL, CPA4, ACE2 ALDH1A1 1754/4885ADH1C 3848/4885ADH1A 3773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.