Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22760115 | 0.87 | MAPT (0.46) | LMNAMAPTKDM4EGAAALDH1A1 | |
| SCHEMBL22760164 | 0.87 | ALDH1A1 (0.38) | TSHRLMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL22760408 | 0.82 | PIM1 (0.42) | TSHRLMNAMAPTKDM4EGAA | |
| SCHEMBL22760215 | 0.82 | HPGD (0.51) | LMNAMAPTGAAALDH1A1MEN1 | |
| SCHEMBL22760162 | 0.82 | TSHR (0.47) | TSHRLMNAMAPTKDM4EGAA | |
| SCHEMBL22747825 | 0.80 | HPGD (0.45) | TSHRLMNAMAPTGAAALDH1A1 | |
| SCHEMBL22760342 | 0.80 | HPGD (0.45) | LMNAMAPTGAAALDH1A1MEN1 | |
| SCHEMBL22760232 | 0.79 | HPGD (0.44) | LMNAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL22760172 | 0.77 | MAPT (0.47) | TSHRLMNAMAPTKDM4EGAA | |
| SCHEMBL22747864 | 0.77 | CCR2 (0.46) | TSHRLMNAMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |